Gene Review:
KDM4A - lysine (K)-specific demethylase 4A
Homo sapiens
Synonyms:
JHDM3A, JMJD2, JMJD2A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, ...
- Identification and characterization of JMJD2 family genes in silico. Katoh, M., Katoh, M. Int. J. Oncol. (2004)
- Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein. Gray, S.G., Iglesias, A.H., Lizcano, F., Villanueva, R., Camelo, S., Jingu, H., Teh, B.T., Koibuchi, N., Chin, W.W., Kokkotou, E., Dangond, F. J. Biol. Chem. (2005)
- Structural insights into histone demethylation by JMJD2 family members. Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Mao, Q., Pan, C.H., Dai, S., Hagman, J., Hansen, K., Shi, Y., Zhang, G. Cell (2006)
- Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Ng, S.S., Kavanagh, K.L., McDonough, M.A., Butler, D., Pilka, E.S., Lienard, B.M., Bray, J.E., Savitsky, P., Gileadi, O., von Delft, F., Rose, N.R., Offer, J., Scheinost, J.C., Borowski, T., Sundstrom, M., Schofield, C.J., Oppermann, U. Nature. (2007)
- Reversal of Histone Lysine Trimethylation by the JMJD2 Family of Histone Demethylases. Whetstine, J.R., Nottke, A., Lan, F., Huarte, M., Smolikov, S., Chen, Z., Spooner, E., Li, E., Zhang, G., Colaiacovo, M., Shi, Y. Cell (2006)
- Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Huang, Y., Fang, J., Bedford, M.T., Zhang, Y., Xu, R.M. Science (2006)
- The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Klose, R.J., Yamane, K., Bae, Y., Zhang, D., Erdjument-Bromage, H., Tempst, P., Wong, J., Zhang, Y. Nature (2006)
- JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2). Zhang, D., Yoon, H.G., Wong, J. Mol. Cell. Biol. (2005)