Gene Review:
RBM8A - RNA binding motif protein 8A
Homo sapiens
Synonyms:
BOV-1, BOV-1A, BOV-1B, BOV-1C, Binder of OVCA1-1, ...
- Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses. Kuhmann, S.E., Platt, E.J., Kozak, S.L., Kabat, D. J. Virol. (1997)
- Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. Kim, V.N., Kataoka, N., Dreyfuss, G. Science (2001)
- 5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly. Reichert, V.L., Le Hir, H., Jurica, M.S., Moore, M.J. Genes Dev. (2002)
- Y14 and hUpf3b form an NMD-activating complex. Gehring, N.H., Neu-Yilik, G., Schell, T., Hentze, M.W., Kulozik, A.E. Mol. Cell (2003)
- Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm. Kataoka, N., Yong, J., Kim, V.N., Velazquez, F., Perkinson, R.A., Wang, F., Dreyfuss, G. Mol. Cell (2000)
- A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q.12. Morgan, K., Conklin, D., Pawson, A.J., Sellar, R., Ott, T.R., Millar, R.P. Endocrinology (2003)
- The genes encoding the type II gonadotropin-releasing hormone receptor and the ribonucleoprotein RBM8A in humans overlap in two genomic loci. Faurholm, B., Millar, R.P., Katz, A.A. Genomics (2001)
- Conserved physical linkage of GnRH-R and RBM8 in the medaka and human genomes. Okubo, K., Mitani, H., Naruse, K., Kondo, M., Shima, A., Tanaka, M., Aida, K. Biochem. Biophys. Res. Commun. (2002)
- The Y14 protein communicates to the cytoplasm the position of exon-exon junctions. Kim, V.N., Yong, J., Kataoka, N., Abel, L., Diem, M.D., Dreyfuss, G. EMBO J. (2001)
- MAGOH interacts with a novel RNA-binding protein. Zhao, X.F., Nowak, N.J., Shows, T.B., Aplan, P.D. Genomics (2000)
- Translation is required to remove Y14 from mRNAs in the cytoplasm. Dostie, J., Dreyfuss, G. Curr. Biol. (2002)
- Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. Islam, S., Montgomery, R.K., Fialkovich, J.J., Grand, R.J. J. Histochem. Cytochem. (2005)
- In vivo BiFC analysis of Y14 and NXF1 mRNA export complexes: preferential localization within and around SC35 domains. Schmidt, U., Richter, K., Berger, A.B., Lichter, P. J. Cell Biol. (2006)
- Phosphorylation of Y14 modulates its interaction with proteins involved in mRNA metabolism and influences its methylation. Hsu, I.a.W., Hsu, M., Li, C., Chuang, T.W., Lin, R.I., Tarn, W.Y. J. Biol. Chem. (2005)
- c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination. Taher, T.E., Tjin, E.P., Beuling, E.A., Borst, J., Spaargaren, M., Pals, S.T. J. Immunol. (2002)
- Recognition of RANTES by Extracellular Parts of the CCR5 Receptor. Duma, L., H??ussinger, D., Rogowski, M., Lusso, P., Grzesiek, S. J. Mol. Biol. (2007)
- Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex. Kataoka, N., Diem, M.D., Kim, V.N., Yong, J., Dreyfuss, G. EMBO J. (2001)
- Sheep exhibit novel variations in the organization of the mammalian type II gonadotropin-releasing hormone receptor gene. Gault, P.M., Morgan, K., Pawson, A.J., Millar, R.P., Lincoln, G.A. Endocrinology (2004)
- The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity. Ballut, L., Marchadier, B., Baguet, A., Tomasetto, C., Séraphin, B., Le Hir, H. Nat. Struct. Mol. Biol. (2005)
- eIF4A3 is a novel component of the exon junction complex. Chan, C.C., Dostie, J., Diem, M.D., Feng, W., Mann, M., Rappsilber, J., Dreyfuss, G. RNA (2004)
- Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor. Salicioni, A.M., Xi, M., Vanderveer, L.A., Balsara, B., Testa, J.R., Dunbrack, R.L., Godwin, A.K. Genomics (2000)
- A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex. Kataoka, N., Dreyfuss, G. J. Biol. Chem. (2004)