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MeSH Review

Dilatation, Pathologic

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Disease relevance of Dilatation, Pathologic


High impact information on Dilatation, Pathologic


Chemical compound and disease context of Dilatation, Pathologic


Biological context of Dilatation, Pathologic


Anatomical context of Dilatation, Pathologic

  • The biosynthesis of prostaglandin E2 in the antrum of the gastric mucosa was significantly higher in cirrhotics with gastric vascular ectasia than in cirrhotics without this lesion (p less than 0.05) and healthy controls (p less than 0.005) [4].
  • We describe a 72-year-old woman with a chronic facial pain, and ectasia and left sided deviation of the basilar artery, that responded dramatically to baclofen [14].
  • SETTING: Department of Cornea and Refractive Surgery, Instituto Oftalmológico de Alicante, and Miguel Hernández University School of Medicine, Alicante, Spain. METHODS: In this prospective noncomparative intervention case series, Intacs segments were implanted in 3 eyes that developed posterior ectasia after myopic LASIK with clear central corneas [15].
  • High myopia is characterized by scleral thinning and localized ectasia of the posterior sclera [16].
  • This meningocele most likely represents a variant of cranial nerve dural ectasia occasionally seen in individuals with NF1 [17].

Gene context of Dilatation, Pathologic

  • At 13 months of age, mammary ductal ectasia was found in CMV-AIB1/ACTR-Delta3 mice, but secondary and tertiary branching patterns were normal [18].
  • CONCLUSIONS: These observations suggest that MMP/TIMP imbalance is present in patients with generalized CE and may contribute to ectasia formation [19].
  • Plasma soluble adhesion molecules; intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin levels in patients with isolated coronary artery ectasia [20].
  • MMP-9 or MMP-12 deficiency conferred significant protection against transmedial elastin degradation and ectasia in the atherosclerotic media [21].
  • However, subgroup analysis demonstrated that MMP-3 level is significantly lower in patients with generalized CEs compared to those with single vessel ectasia [19].

Analytical, diagnostic and therapeutic context of Dilatation, Pathologic


  1. Genetic linkage of the Marfan syndrome, ectopia lentis, and congenital contractural arachnodactyly to the fibrillin genes on chromosomes 15 and 5. The International Marfan Syndrome Collaborative Study. Tsipouras, P., Del Mastro, R., Sarfarazi, M., Lee, B., Vitale, E., Child, A.H., Godfrey, M., Devereux, R.B., Hewett, D., Steinmann, B. N. Engl. J. Med. (1992) [Pubmed]
  2. Cholesterol granuloma of the breast: a mimic of carcinoma. Reynolds, H.E., Cramer, H.M. Radiology. (1994) [Pubmed]
  3. Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Sweeney, W.E., Hamahira, K., Sweeney, J., Garcia-Gatrell, M., Frost, P., Avner, E.D. Kidney Int. (2003) [Pubmed]
  4. Increased gastric PGE2 biosynthesis in cirrhotic patients with gastric vascular ectasia. Saperas, E., Perez Ayuso, R.M., Poca, E., Bordas, J.M., Gaya, J., Pique, J.M. Am. J. Gastroenterol. (1990) [Pubmed]
  5. Pedal hemangiomas versus vascular ectasia in Turner syndrome. Bushkell, L.L., Broughton, R.A. J. Pediatr. (1984) [Pubmed]
  6. Hyperprolactinemia and nonpuerperal mastitis (duct ectasia). Peters, F., Schuth, W. JAMA (1989) [Pubmed]
  7. Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells. Abrams, J.R., Kelley, S.L., Hayes, E., Kikuchi, T., Brown, M.J., Kang, S., Lebwohl, M.G., Guzzo, C.A., Jegasothy, B.V., Linsley, P.S., Krueger, J.G. J. Exp. Med. (2000) [Pubmed]
  8. Images in cardiovascular medicine. Coronary artery ectasia and systolic flow cessation in hypertrophic cardiomyopathy. Gielen, S., Strasser, R.H., Kübler, W., Haller, C. Circulation (1998) [Pubmed]
  9. Increased prevalence of coronary ectasia in heterozygous familial hypercholesterolemia. Sudhir, K., Ports, T.A., Amidon, T.M., Goldberger, J.J., Bhushan, V., Kane, J.P., Yock, P., Malloy, M.J. Circulation (1995) [Pubmed]
  10. Minocycline hydrochloride hyperpigmentation complicating treatment of venous ectasia of the extremities. Leffell, D.J. J. Am. Acad. Dermatol. (1991) [Pubmed]
  11. Essential progressive telangiectasia in an autoimmune setting: successful treatment with acyclovir. Shelley, W.B., Shelley, E.D. J. Am. Acad. Dermatol. (1989) [Pubmed]
  12. Electrophysiological laboratory, electrophysiologist-implanted, nonthoracotomy-implantable cardioverter/defibrillators. Fitzpatrick, A.P., Lesh, M.D., Epstein, L.M., Lee, R.J., Siu, A., Merrick, S., Griffin, J.C., Scheinman, M.M. Circulation (1994) [Pubmed]
  13. The role of angiotensin converting enzyme genotype in coronary artery ectasia. Uyarel, H., Okmen, E., Tartan, Z., Kasikcioglu, H., Dayi, S.U., Karabulut, A., Uzunlar, B., Samur, H., Cam, N. International heart journal. (2005) [Pubmed]
  14. Atypical facial pain, ectasia of the basilar artery, and baclofen: a case report. Martins, I.P., Ferro, J.M. Headache. (1989) [Pubmed]
  15. Intracorneal rings to correct corneal ectasia after laser in situ keratomileusis. Alió, J., Salem, T., Artola, A., Osman, A. Journal of cataract and refractive surgery. (2002) [Pubmed]
  16. The sclera and myopia. Rada, J.A., Shelton, S., Norton, T.T. Exp. Eye Res. (2006) [Pubmed]
  17. An unusual pterygopalatine meningocele associated with neurofibromatosis type 1. Case report. Chapman, P.H., Curtin, H.D., Cunningham, M.J. J. Neurosurg. (2000) [Pubmed]
  18. Overexpression of an N-terminally truncated isoform of the nuclear receptor coactivator amplified in breast cancer 1 leads to altered proliferation of mammary epithelial cells in transgenic mice. Tilli, M.T., Reiter, R., Oh, A.S., Henke, R.T., McDonnell, K., Gallicano, G.I., Furth, P.A., Riegel, A.T. Mol. Endocrinol. (2005) [Pubmed]
  19. Temporal association between circulating proteolytic, inflammatory and neurohormonal markers in patients with coronary ectasia. Finkelstein, A., Michowitz, Y., Abashidze, A., Miller, H., Keren, G., George, J. Atherosclerosis (2005) [Pubmed]
  20. Plasma soluble adhesion molecules; intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin levels in patients with isolated coronary artery ectasia. Turhan, H., Erbay, A.R., Yasar, A.S., Aksoy, Y., Bicer, A., Yetkin, G., Yetkin, E. Coron. Artery Dis. (2005) [Pubmed]
  21. Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth. Luttun, A., Lutgens, E., Manderveld, A., Maris, K., Collen, D., Carmeliet, P., Moons, L. Circulation (2004) [Pubmed]
  22. Association of coronary artery ectasia with plasma insulin levels in Japanese men of heterozygous familial hypercholesterolemia with the low-density lipoprotein receptor gene mutation K790X. Murase, Y., Yagi, K., Kobayashi, J., Nohara, A., Asano, A., Koizumi, J., Mabuchi, H. Clin. Chim. Acta (2005) [Pubmed]
  23. Use of tolazoline enahanced superior mesenteric arteriography to improve opacification of a cecal vascular ectasia: a case report. Sniderman, K.W., Baxi, R.K., Saddekni, S., Sos, T.A. Gastrointestinal radiology. (1979) [Pubmed]
  24. Evaluation of the effect of trimetazidine on Tc-99m methoxyisobutyl isonitrile gated scintigraphy in patients with coronary artery ectasia. Okudan, B., Ozbek, F.M., Dogan, A., Ozturk, B., Yildiz, M. Saudi medical journal. (2005) [Pubmed]
  25. Hospitalisation of prostatic cancer patients undergoing orchiectomy. Johansen, T.E., Fjaere, H.T. British journal of urology. (1991) [Pubmed]
  26. Corneal ectasia after photorefractive keratectomy for low myopia. Malecaze, F., Coullet, J., Calvas, P., Fournié, P., Arné, J.L., Brodaty, C. Ophthalmology (2006) [Pubmed]
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