MeSH Review:
Gene Deletion
Forger,
Rosen,
Waters,
Jacob,
Simerly,
de Vries,
Shimizu,
Hashimoto,
Kobayashi,
Mitsumori,
Ohgake,
Koizumi,
Okamura,
Koike,
Kumakiri,
Nakazato,
Komatsu,
Iyo,
Olson,
Srivastava,
Thomas,
Lin,
Kirby,
Brown,
Olson,
Novelli,
Amati,
Dallapiccola,
Bitner-Glindzicz,
Lindley,
Rutland,
Blaydon,
Smith,
Milla,
Hussain,
Furth-Lavi,
Cosgrove,
Shepherd,
Barnes,
O'Brien,
Farndon,
Sowden,
Liu,
Scanlan,
Malcolm,
Dunne,
Aynsley-Green,
Glaser,
- Effect of dystrophin gene deletions on mRNA levels and processing in Duchenne and Becker muscular dystrophies. Chelly, J., Gilgenkrantz, H., Lambert, M., Hamard, G., Chafey, P., Récan, D., Katz, P., de la Chapelle, A., Koenig, M., Ginjaar, I.B. Cell (1990)
- Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone. Zhao, R., Davey, M., Hsu, Y.C., Kaplanek, P., Tong, A., Parsons, A.B., Krogan, N., Cagney, G., Mai, D., Greenblatt, J., Boone, C., Emili, A., Houry, W.A. Cell (2005)
- Glutathione S-transferase mu and theta polymorphisms and breast cancer susceptibility. García-Closas, M., Kelsey, K.T., Hankinson, S.E., Spiegelman, D., Springer, K., Willett, W.C., Speizer, F.E., Hunter, D.J. J. Natl. Cancer Inst. (1999)
- Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency. Faury, G., Pezet, M., Knutsen, R.H., Boyle, W.A., Heximer, S.P., McLean, S.E., Minkes, R.K., Blumer, K.J., Kovacs, A., Kelly, D.P., Li, D.Y., Starcher, B., Mecham, R.P. J. Clin. Invest. (2003)
- Early-onset autoimmune hepatitis is associated with a C4A gene deletion. Scully, L.J., Toze, C., Sengar, D.P., Goldstein, R. Gastroenterology (1993)
- Endogenous neurotrophin-3 supports the survival of a subpopulation of sensory neurons in neonatal rat. Zhou, X.F., Cameron, D., Rush, R.A. Neuroscience (1998)
- Interstitial deletion of 11(p11.2p12): a newly described contiguous gene deletion syndrome involving the gene for hereditary multiple exostoses (EXT2). Potocki, L., Shaffer, L.G. Am. J. Med. Genet. (1996)
- Lack of association between angiotensin I-converting enzyme insertion/deletion gene functional polymorphism and panic disorder in humans. Shimizu, E., Hashimoto, K., Kobayashi, K., Mitsumori, M., Ohgake, S., Koizumi, H., Okamura, N., Koike, K., Kumakiri, C., Nakazato, M., Komatsu, N., Iyo, M. Neurosci. Lett. (2004)
- Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Liu, L., Yan, Y., Zeng, M., Zhang, J., Hanes, M.A., Ahearn, G., McMahon, T.J., Dickfeld, T., Marshall, H.E., Que, L.G., Stamler, J.S. Cell (2004)
- A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene. Bitner-Glindzicz, M., Lindley, K.J., Rutland, P., Blaydon, D., Smith, V.V., Milla, P.J., Hussain, K., Furth-Lavi, J., Cosgrove, K.E., Shepherd, R.M., Barnes, P.D., O'Brien, R.E., Farndon, P.A., Sowden, J., Liu, X.Z., Scanlan, M.J., Malcolm, S., Dunne, M.J., Aynsley-Green, A., Glaser, B. Nat. Genet. (2000)
- Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Srivastava, D., Thomas, T., Lin, Q., Kirby, M.L., Brown, D., Olson, E.N. Nat. Genet. (1997)
- Emerin deletion reveals a common X-chromosome inversion mediated by inverted repeats. Small, K., Iber, J., Warren, S.T. Nat. Genet. (1997)
- The mottled gene is the mouse homologue of the Menkes disease gene. Levinson, B., Vulpe, C., Elder, B., Martin, C., Verley, F., Packman, S., Gitschier, J. Nat. Genet. (1994)
- Glutathione S-transferase gene deletions in myelodysplasia. Atoyebi, W., Kusec, R., Fidler, C., Peto, T.E., Boultwood, J., Wainscoat, J.S. Lancet (1997)
- The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion. Kato, K., Kanaji, T., Russell, S., Kunicki, T.J., Furihata, K., Kanaji, S., Marchese, P., Reininger, A., Ruggeri, Z.M., Ware, J. Blood (2003)
- Angiotensin II type 1 receptor A1166C gene polymorphism. Absence of an association with the risk of coronary artery disease and myocardial infarction and of a synergistic effect with angiotensin-converting enzyme gene polymorphism on the risk of these diseases. Gardemann, A., Nguyen, Q.D., Humme, J., Stricker, J., Katz, N., Tillmanns, H., Hehrlein, F.W., Rau, M., Haberbosch, W. Eur. Heart J. (1998)
- Determination of deletion sizes in the MHC-linked complement C4 and steroid 21-hydroxylase genes by pulsed-field gel electrophoresis. Partanen, J., Kere, J., Wessberg, S., Koskimies, S. Genomics (1989)
- Rb and p53 gene deletions in lung adenocarcinomas from irradiated and control mice. Zhang, Y., Woloschak, G.E. Radiat. Res. (1997)
- Preimplantation single cell analyses of dystrophin gene deletions using whole genome amplification. Kristjansson, K., Chong, S.S., Van den Veyver, I.B., Subramanian, S., Snabes, M.C., Hughes, M.R. Nat. Genet. (1994)
- The deletion in a type of delta 0-beta 0-thalassaemia begins in an inverted AluI repeat. Ottolenghi, S., Giglioni, B. Nature (1982)
- The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters. Brodeur, P.H., Osman, G.E., Mackle, J.J., Lalor, T.M. J. Exp. Med. (1988)
- PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. Crosson, S.M., Khan, A., Printen, J., Pessin, J.E., Saltiel, A.R. J. Clin. Invest. (2003)
- UFD1L and CDC45L: a role in DiGeorge syndrome and related phenotypes? Novelli, G., Amati, F., Dallapiccola, B. Trends Genet. (1999)
- Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes. Breit, T.M., Mol, E.J., Wolvers-Tettero, I.L., Ludwig, W.D., van Wering, E.R., van Dongen, J.J. J. Exp. Med. (1993)
- Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha. Flesch, I.E., Hess, J.H., Huang, S., Aguet, M., Rothe, J., Bluethmann, H., Kaufmann, S.H. J. Exp. Med. (1995)
- Illegitimate transcription. Application to the analysis of truncated transcripts of the dystrophin gene in nonmuscle cultured cells from Duchenne and Becker patients. Chelly, J., Gilgenkrantz, H., Hugnot, J.P., Hamard, G., Lambert, M., Récan, D., Akli, S., Cometto, M., Kahn, A., Kaplan, J.C. J. Clin. Invest. (1991)
- Undermining the endothelium by ablation of MAPK-MEF2 signaling. Olson, E.N. J. Clin. Invest. (2004)
- Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice. Fukaya, M., Kato, A., Lovett, C., Tonegawa, S., Watanabe, M. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Deficiencies of human complement component C4A and C4B and heterozygosity in length variants of RP-C4-CYP21-TNX (RCCX) modules in caucasians. The load of RCCX genetic diversity on major histocompatibility complex-associated disease. Blanchong, C.A., Zhou, B., Rupert, K.L., Chung, E.K., Jones, K.N., Sotos, J.F., Zipf, W.B., Rennebohm, R.M., Yung Yu, C. J. Exp. Med. (2000)
- Null alleles of human complement C4. Evidence for pseudogenes at the C4A locus and for gene conversion at the C4B locus. Braun, L., Schneider, P.M., Giles, C.M., Bertrams, J., Rittner, C. J. Exp. Med. (1990)
- Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency. Volanakis, J.E., Zhu, Z.B., Schaffer, F.M., Macon, K.J., Palermos, J., Barger, B.O., Go, R., Campbell, R.D., Schroeder, H.W., Cooper, M.D. J. Clin. Invest. (1992)
- Specific genetic deficiencies of the A and B isoenzymes of monoamine oxidase are characterized by distinct neurochemical and clinical phenotypes. Lenders, J.W., Eisenhofer, G., Abeling, N.G., Berger, W., Murphy, D.L., Konings, C.H., Wagemakers, L.M., Kopin, I.J., Karoum, F., van Gennip, A.H., Brunner, H.G. J. Clin. Invest. (1996)
- Disruption of mannose activation in Leishmania mexicana: GDP-mannose pyrophosphorylase is required for virulence, but not for viability. Garami, A., Ilg, T. EMBO J. (2001)
- Heart transplants in interferon-gamma, interleukin 4, and interleukin 10 knockout mice. Recipient environment alters graft rejection. Räisänen-Sokolowski, A., Mottram, P.L., Glysing-Jensen, T., Satoskar, A., Russell, M.E. J. Clin. Invest. (1997)
- Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. Pohlenz, J., Dumitrescu, A., Zundel, D., Martiné, U., Schönberger, W., Koo, E., Weiss, R.E., Cohen, R.N., Kimura, S., Refetoff, S. J. Clin. Invest. (2002)
- Pulsed field gel electrophoresis identifies a high degree of variability in the number of tandem 21-hydroxylase and complement C4 gene repeats in 21-hydroxylase deficiency haplotypes. Collier, S., Sinnott, P.J., Dyer, P.A., Price, D.A., Harris, R., Strachan, T. EMBO J. (1989)
- The cytosolic DnaJ-like protein djp1p is involved specifically in peroxisomal protein import. Hettema, E.H., Ruigrok, C.C., Koerkamp, M.G., van den Berg, M., Tabak, H.F., Distel, B., Braakman, I. J. Cell Biol. (1998)
- Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway. Zhou, X.P., Waite, K.A., Pilarski, R., Hampel, H., Fernandez, M.J., Bos, C., Dasouki, M., Feldman, G.L., Greenberg, L.A., Ivanovich, J., Matloff, E., Patterson, A., Pierpont, M.E., Russo, D., Nassif, N.T., Eng, C. Am. J. Hum. Genet. (2003)
- The haptoglobin-gene deletion responsible for anhaptoglobinemia. Koda, Y., Soejima, M., Yoshioka, N., Kimura, H. Am. J. Hum. Genet. (1998)
- Deletion of Bax eliminates sex differences in the mouse forebrain. Forger, N.G., Rosen, G.J., Waters, E.M., Jacob, D., Simerly, R.B., de Vries, G.J. Proc. Natl. Acad. Sci. U.S.A. (2004)
- The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis. Myers, L.K., Kang, A.H., Postlethwaite, A.E., Rosloniec, E.F., Morham, S.G., Shlopov, B.V., Goorha, S., Ballou, L.R. Arthritis Rheum. (2000)
- Preprotachykinin-A gene products are key mediators of lung injury in polymicrobial sepsis. Puneet, P., Hegde, A., Ng, S.W., Lau, H.Y., Lu, J., Moochhala, S.M., Bhatia, M. J. Immunol. (2006)
- Increased levels of p21WAF1/Cip1 in human brain tumors. Jung, J.M., Bruner, J.M., Ruan, S., Langford, L.A., Kyritsis, A.P., Kobayashi, T., Levin, V.A., Zhang, W. Oncogene (1995)