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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Antigen Presentation

 
 
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Disease relevance of Antigen Presentation

 

High impact information on Antigen Presentation

 

Chemical compound and disease context of Antigen Presentation

 

Biological context of Antigen Presentation

 

Anatomical context of Antigen Presentation

  • These class II MHC-rich, multivesicular endosomes receive incoming antigen and can support not only antigen processing and class II MHC peptide loading but also the export of peptide/class II MHC complexes to the cell surface [21].
  • MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation [22].
  • The transporter associated with the antigen processing 1 (TAP1) gene encodes a subunit for a transporter, presumed to be involved in the delivery of peptides across the endoplasmic reticulum membrane to class I molecules [23].
  • This discrepancy is generally explained by the idea that IFN-gamma either directly activates macrophages, or, by increasing antigen presentation, indirectly activates T cells within the lesions of atherosclerosis and graft arteriosclerosis [24].
  • Evidence for such a function has come from the rescue of class I surface expression by a cloned copy of the human homologue of Ham-1, PSF-1, in a human cell line that is defective in antigen processing [25].
 

Associations of Antigen Presentation with chemical compounds

 

Gene context of Antigen Presentation

 

Analytical, diagnostic and therapeutic context of Antigen Presentation

References

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