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MeSH Review

Fibroadenoma

 
 
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Disease relevance of Fibroadenoma

 

Psychiatry related information on Fibroadenoma

 

High impact information on Fibroadenoma

 

Chemical compound and disease context of Fibroadenoma

 

Biological context of Fibroadenoma

 

Anatomical context of Fibroadenoma

 

Gene context of Fibroadenoma

  • The level of expression of Wnt2 and Wnt4 was 10- to 20-fold higher in fibroadenomas than it was in normal or malignant breast tissue, and in 10% of tumors Wnt7b expression was 30-fold higher than in normal or benign breast tissues [26].
  • Using newly developed quantitative activity assays, the levels of active MMP-2, total (active and activatable) MMP-2 and total MMP-9 were found to be significantly higher in breast carcinomas than in fibroadenomas [27].
  • EGFR was regularly expressed preferentially in the myoepithelial cells of mammary ducts in the fibroadenomas and in nontumorous glands [28].
  • Most fibroadenomas showed weak positivity for ET-1 (83%) and ET-3 (67%) [29].
  • The aim of this study was to evaluate the distribution of aFGF and FGFR4 in specific cell types of fibroadenomas to understand their possible role in the growth of these breast lesions [30].
 

Analytical, diagnostic and therapeutic context of Fibroadenoma

References

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  30. Expression of acidic fibroblast growth factor (aFGF) and fibroblast growth factor receptor 4 (FGFR4) in breast fibroadenomas. La Rosa, S., Sessa, F., Colombo, L., Tibiletti, M.G., Furlan, D., Capella, C. J. Clin. Pathol. (2001) [Pubmed]
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