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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Hydrolysis

 
 
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Disease relevance of Hydrolysis

 

Psychiatry related information on Hydrolysis

 

High impact information on Hydrolysis

 

Chemical compound and disease context of Hydrolysis

 

Biological context of Hydrolysis

 

Anatomical context of Hydrolysis

  • The ATP-binding cassette (ABC) transporters are a family of large proteins in membranes and are able to transport a variety of compounds through membranes against steep concentration gradients at the cost of ATP hydrolysis [26].
  • The EC50 for IL-1 was 28 fM, and PC hydrolysis was detectable within 5 sec at 37 degrees C. The murine cell line had typical high-affinity IL-1 receptors (kd = 7 X 10(-11) M) [27].
  • However, after nucleotide hydrolysis is inhibited by vanadate, unidirectional translocation ceases, and microtubules instead undergo irregular back-and-forth motion along their longitudinal axes [28].
  • The question of whether a G protein couples TCR/CD3 to PI hydrolysis and to Ca2+ mobilization is unresolved, although some indirect evidence for the involvement of GTP binding proteins in T cell activation has recently been obtained with cholera toxin [29].
  • The number of elongating form A and B RNA polymerases in chick oviduct nuclei was estimated by measuring incorportaion of 3H-UTP into 3' termini of nascent RNA chains in the presence of heparin to inhibit initiation, and quantitation labeled uridine released from these termini after alkaline hydrolysis [30].
 

Associations of Hydrolysis with chemical compounds

 

Gene context of Hydrolysis

 

Analytical, diagnostic and therapeutic context of Hydrolysis

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