MeSH Review:
Alzheimer Disease
- Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. Rumble, B., Retallack, R., Hilbich, C., Simms, G., Multhaup, G., Martins, R., Hockey, A., Montgomery, P., Beyreuther, K., Masters, C.L. N. Engl. J. Med. (1989)
- APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism. Kamboh, M.I., Sanghera, D.K., Ferrell, R.E., DeKosky, S.T. Nat. Genet. (1995)
- APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Rovelet-Lecrux, A., Hannequin, D., Raux, G., Le Meur, N., Laquerrière, A., Vital, A., Dumanchin, C., Feuillette, S., Brice, A., Vercelletto, M., Dubas, F., Frebourg, T., Campion, D. Nat. Genet. (2006)
- A Ca(2+) switch aligns the active site of calpain. Moldoveanu, T., Hosfield, C.M., Lim, D., Elce, J.S., Jia, Z., Davies, P.L. Cell (2002)
- Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts. Paloneva, J., Kestilä, M., Wu, J., Salminen, A., Böhling, T., Ruotsalainen, V., Hakola, P., Bakker, A.B., Phillips, J.H., Pekkarinen, P., Lanier, L.L., Timonen, T., Peltonen, L. Nat. Genet. (2000)
- The role of novel chitin-like polysaccharides in Alzheimer disease. Castellani, R.J., Perry, G., Smith, M.A. Neurotox. Res (2007)
- Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. Reiman, E.M., Caselli, R.J., Yun, L.S., Chen, K., Bandy, D., Minoshima, S., Thibodeau, S.N., Osborne, D. N. Engl. J. Med. (1996)
- Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. Rothstein, J.D., Martin, L.J., Kuncl, R.W. N. Engl. J. Med. (1992)
- Amyloid beta vaccination: reduced plaques and improved cognition. Younkin, S.G. Nat. Med. (2001)
- Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Hofman, A., Ott, A., Breteler, M.M., Bots, M.L., Slooter, A.J., van Harskamp, F., van Duijn, C.N., Van Broeckhoven, C., Grobbee, D.E. Lancet (1997)
- High-density lipoprotein cholesterol in differential diagnosis of senile dementia. Muckle, T.J., Roy, J.R. Lancet (1985)
- Endocytosis. Mukherjee, S., Ghosh, R.N., Maxfield, F.R. Physiol. Rev. (1997)
- Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Tanzi, R.E., Bertram, L. Cell (2005)
- Secrets of a secretase: N-cadherin proteolysis regulates CBP function. Rao, V.R., Finkbeiner, S. Cell (2003)
- A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Marambaud, P., Wen, P.H., Dutt, A., Shioi, J., Takashima, A., Siman, R., Robakis, N.K. Cell (2003)
- Patterns of brain activation in people at risk for Alzheimer's disease. Bookheimer, S.Y., Strojwas, M.H., Cohen, M.S., Saunders, A.M., Pericak-Vance, M.A., Mazziotta, J.C., Small, G.W. N. Engl. J. Med. (2000)
- Tacrine in Alzheimer's disease. Gracon, S.I. N. Engl. J. Med. (1993)
- The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. LaFerla, F.M., Tinkle, B.T., Bieberich, C.J., Haudenschild, C.C., Jay, G. Nat. Genet. (1995)
- Glutamate/aspartate-releasing neurons in Alzheimer's disease. Procter, A.W., Palmer, A.M., Stratmann, G.C., Bowen, D.M. N. Engl. J. Med. (1986)
- Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type. Summers, W.K., Majovski, L.V., Marsh, G.M., Tachiki, K., Kling, A. N. Engl. J. Med. (1986)
- Choline in Alzheimer's disease. Renvoize, E.B., Jerram, T. N. Engl. J. Med. (1979)
- Cholesterol metabolism, apolipoprotein E, adenosine triphosphate-binding cassette transporters, and Alzheimer's disease. Hirsch-Reinshagen, V., Wellington, C.L. Curr. Opin. Lipidol. (2007)
- Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease. Mayeux, R., Saunders, A.M., Shea, S., Mirra, S., Evans, D., Roses, A.D., Hyman, B.T., Crain, B., Tang, M.X., Phelps, C.H. N. Engl. J. Med. (1998)
- A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene. Mullan, M., Houlden, H., Windelspecht, M., Fidani, L., Lombardi, C., Diaz, P., Rossor, M., Crook, R., Hardy, J., Duff, K. Nat. Genet. (1992)
- beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Zheng, H., Jiang, M., Trumbauer, M.E., Sirinathsinghji, D.J., Hopkins, R., Smith, D.W., Heavens, R.P., Dawson, G.R., Boyce, S., Conner, M.W., Stevens, K.A., Slunt, H.H., Sisoda, S.S., Chen, H.Y., Van der Ploeg, L.H. Cell (1995)
- Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Weidemann, A., König, G., Bunke, D., Fischer, P., Salbaum, J.M., Masters, C.L., Beyreuther, K. Cell (1989)
- Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Goedert, M., Jakes, R., Spillantini, M.G., Hasegawa, M., Smith, M.J., Crowther, R.A. Nature (1996)
- Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families. Van Broeckhoven, C., Genthe, A.M., Vandenberghe, A., Horsthemke, B., Backhovens, H., Raeymaekers, P., Van Hul, W., Wehnert, A., Gheuens, J., Cras, P. Nature (1987)
- Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Tsirka, S.E., Gualandris, A., Amaral, D.G., Strickland, S. Nature (1995)
- Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Wolfe, M.S., Xia, W., Ostaszewski, B.L., Diehl, T.S., Kimberly, W.T., Selkoe, D.J. Nature (1999)
- Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Bard, F., Cannon, C., Barbour, R., Burke, R.L., Games, D., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., Kholodenko, D., Lee, M., Lieberburg, I., Motter, R., Nguyen, M., Soriano, F., Vasquez, N., Weiss, K., Welch, B., Seubert, P., Schenk, D., Yednock, T. Nat. Med. (2000)
- Amyloid beta-protein deposition in tissues other than brain in Alzheimer's disease. Joachim, C.L., Mori, H., Selkoe, D.J. Nature (1989)
- Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease. Okuizumi, K., Onodera, O., Namba, Y., Ikeda, K., Yamamoto, T., Seki, K., Ueki, A., Nanko, S., Tanaka, H., Takahashi, H., Oyanagi, K., Mizusawa, H., Kanazawa, I., Tsuji, S. Nat. Genet. (1995)
- Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., Kholodenko, D., Lee, M., Liao, Z., Lieberburg, I., Motter, R., Mutter, L., Soriano, F., Shopp, G., Vasquez, N., Vandevert, C., Walker, S., Wogulis, M., Yednock, T., Games, D., Seubert, P. Nature (1999)
- Apolipoprotein E and Alzheimer's disease. Strittmatter, W.J., Roses, A.D. Annu. Rev. Neurosci. (1996)
- Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis. Carter, C.J. Neurochem. Int. (2007)
- A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group. Davis, K.L., Thal, L.J., Gamzu, E.R., Davis, C.S., Woolson, R.F., Gracon, S.I., Drachman, D.A., Schneider, L.S., Whitehouse, P.J., Hoover, T.M. N. Engl. J. Med. (1992)
- A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Morgan, D., Diamond, D.M., Gottschall, P.E., Ugen, K.E., Dickey, C., Hardy, J., Duff, K., Jantzen, P., DiCarlo, G., Wilcock, D., Connor, K., Hatcher, J., Hope, C., Gordon, M., Arendash, G.W. Nature (2000)