The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Ectromelia, Infectious

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Ectromelia, Infectious

  • Here, we report the expression of a functional soluble CD30 homologue, viral CD30 (vCD30), encoded by ectromelia (mousepox) virus, a poxvirus that causes a severe disease related to human smallpox [1].
  • Variola virus, the causative agent of smallpox in humans, and ECTV, which causes mousepox in mice, both encode receptor homologs that are thought to interfere with host IFN function [2].
 

High impact information on Ectromelia, Infectious

 

Gene context of Ectromelia, Infectious

  • Mousepox was identified in a single mouse-holding room in early 1999 after a group of 20 CAF1/Hsd mice were inoculated SC with a killed murine spindle cell tumor line, S1509A [8].

References

  1. Inhibition of type 1 cytokine-mediated inflammation by a soluble CD30 homologue encoded by ectromelia (mousepox) virus. Saraiva, M., Smith, P., Fallon, P.G., Alcami, A. J. Exp. Med. (2002) [Pubmed]
  2. Interferon function is not required for recovery from a secondary poxvirus infection. Panchanathan, V., Chaudhri, G., Karupiah, G. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  3. Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox. Jackson, R.J., Ramsay, A.J., Christensen, C.D., Beaton, S., Hall, D.F., Ramshaw, I.A. J. Virol. (2001) [Pubmed]
  4. Chromosome mapping of Rmp-4, a gonad-dependent gene encoding host resistance to mousepox. Brownstein, D.G., Gras, L. J. Virol. (1995) [Pubmed]
  5. Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3. Brownstein, D.G., Bhatt, P.N., Gras, L., Budris, T. J. Virol. (1992) [Pubmed]
  6. Biosynthesis of the IFN-gamma binding protein of ectromelia virus, the causative agent of mousepox. Bai, H., Buller, R.M., Chen, N., Green, M., Nuara, A.A. Virology (2005) [Pubmed]
  7. Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model. Buller, R.M., Owens, G., Schriewer, J., Melman, L., Beadle, J.R., Hostetler, K.Y. Virology (2004) [Pubmed]
  8. Mousepox resulting from use of ectromelia virus-contaminated, imported mouse serum. Lipman, N.S., Perkins, S., Nguyen, H., Pfeffer, M., Meyer, H. Comp. Med. (2000) [Pubmed]
 
WikiGenes - Universities