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MeSH Review

Asthma

 
 
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Disease relevance of Asthma

 

Psychiatry related information on Asthma

 

High impact information on Asthma

 

Chemical compound and disease context of Asthma

 

Biological context of Asthma

 

Anatomical context of Asthma

  • In bronchial asthma, considerable evidence exists that the eosinophil releases granule proteins, especially the major basic protein (MBP), which in turn mediate tissue abnormalities [24].
  • CONCLUSIONS: This study demonstrates that induced sputum can be used to detect mRNA for TH2 -type cytokines in bronchial asthma and that the increase in IL-4 and IL-5 mRNA expression is similar to that seen with more invasive techniques [25].
  • RESULTS: IL-4-induced expression of CD23 on B cells was greater in normal atopic subjects and atopic patients with bronchial asthma than in normal nonatopic subjects [26].
  • OBJECTIVES: The aim of this study was to investigate the regulatory mechanisms of chemokine production from bronchial epithelium by inflammatory cytokines, especially T(H)2- and T(H)1-derived cytokines, in bronchial asthma [27].
  • These results show that the increased CytOx activity previously reported in skeletal muscle of patients with COPD is also detected in other cell types (such as circulating lymphocytes) and in other chronic inflammatory diseases (such as bronchial asthma and chronic arthritis) [28].
 

Gene context of Asthma

 

Analytical, diagnostic and therapeutic context of Asthma

References

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  23. Cat is a major allergen in patients with asthma from west Siberia, Russia. Gusareva, E.S., Bragina, E.J., Deeva, E.V., Kazakevich, N.V., Puzyrev, V.P., Ogorodova, L.M., Lipoldová, M. Allergy. (2006) [Pubmed]
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