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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

DNA Methylation

 
 
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Disease relevance of DNA Methylation

 

Psychiatry related information on DNA Methylation

 

High impact information on DNA Methylation

 

Chemical compound and disease context of DNA Methylation

 

Biological context of DNA Methylation

 

Anatomical context of DNA Methylation

 

Associations of DNA Methylation with chemical compounds

 

Gene context of DNA Methylation

  • We show here that the chief enzyme that maintains mammalian DNA methylation, DNMT1, can also establish a repressive transcription complex [32].
  • To define the mechanism through which demethylated cells die, and to establish a paradigm for identifying genes regulated by DNA methylation, we have generated mice with a conditional allele for the maintenance DNA methyltransferase gene Dnmt1 [33].
  • We suggest that the process of DNA methylation, mediated by Dnmt1, may depend on or generate an altered chromatin state via histone deacetylase activity [34].
  • Regulation of DNA methylation of Rasgrf1 [35].
  • Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation [36].
 

Analytical, diagnostic and therapeutic context of DNA Methylation

References

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  31. Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa. Tamaru, H., Zhang, X., McMillen, D., Singh, P.B., Nakayama, J., Grewal, S.I., Allis, C.D., Cheng, X., Selker, E.U. Nat. Genet. (2003) [Pubmed]
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