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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Genetic Predisposition to Disease

 
 
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Disease relevance of Genetic Predisposition to Disease

 

Psychiatry related information on Genetic Predisposition to Disease

 

High impact information on Genetic Predisposition to Disease

 

Chemical compound and disease context of Genetic Predisposition to Disease

 

Biological context of Genetic Predisposition to Disease

 

Anatomical context of Genetic Predisposition to Disease

 

Associations of Genetic Predisposition to Disease with chemical compounds

 

Gene context of Genetic Predisposition to Disease

 

Analytical, diagnostic and therapeutic context of Genetic Predisposition to Disease

References

  1. Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Bell, D.W., Gore, I., Okimoto, R.A., Godin-Heymann, N., Sordella, R., Mulloy, R., Sharma, S.V., Brannigan, B.W., Mohapatra, G., Settleman, J., Haber, D.A. Nat. Genet. (2005) [Pubmed]
  2. Heterozygous ATM mutations do not contribute to early onset of breast cancer. FitzGerald, M.G., Bean, J.M., Hegde, S.R., Unsal, H., MacDonald, D.J., Harkin, D.P., Finkelstein, D.M., Isselbacher, K.J., Haber, D.A. Nat. Genet. (1997) [Pubmed]
  3. A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia. Kuo, H.C., Cheng, C.F., Clark, R.B., Lin, J.J., Lin, J.L., Hoshijima, M., Nguyêñ-Trân, V.T., Gu, Y., Ikeda, Y., Chu, P.H., Ross, J., Giles, W.R., Chien, K.R. Cell (2001) [Pubmed]
  4. The beta-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus. Glaser, T., Lewis, W.H., Bruns, G.A., Watkins, P.C., Rogler, C.E., Shows, T.B., Powers, V.E., Willard, H.F., Goguen, J.M., Simola, K.O. Nature (1986) [Pubmed]
  5. Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function. Tomer, Y., Davies, T.F. Endocr. Rev. (2003) [Pubmed]
  6. Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease. Collinge, J., Palmer, M.S., Dryden, A.J. Lancet (1991) [Pubmed]
  7. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Karayiorgou, M., Altemus, M., Galke, B.L., Goldman, D., Murphy, D.L., Ott, J., Gogos, J.A. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  8. Basal and adenosine receptor-stimulated levels of cAMP are reduced in lymphocytes from alcoholic patients. Diamond, I., Wrubel, B., Estrin, W., Gordon, A. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  9. Distortion of allelic expression of apolipoprotein E in Alzheimer's disease. Lambert, J.C., Pérez-Tur, J., Dupire, M.J., Galasko, D., Mann, D., Amouyel, P., Hardy, J., Delacourte, A., Chartier-Harlin, M.C. Hum. Mol. Genet. (1997) [Pubmed]
  10. Variation in the ESR1 and ESR2 genes and genetic susceptibility to anorexia nervosa. Eastwood, H., Brown, K.M., Markovic, D., Pieri, L.F. Mol. Psychiatry (2002) [Pubmed]
  11. Genetic susceptibility to systemic lupus erythematosus. Vyse, T.J., Kotzin, B.L. Annu. Rev. Immunol. (1998) [Pubmed]
  12. The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor. Hershey, G.K., Friedrich, M.F., Esswein, L.A., Thomas, M.L., Chatila, T.A. N. Engl. J. Med. (1997) [Pubmed]
  13. A putative vulnerability locus to multiple sclerosis maps to 5p14-p12 in a region syntenic to the murine locus Eae2. Kuokkanen, S., Sundvall, M., Terwilliger, J.D., Tienari, P.J., Wikström, J., Holmdahl, R., Pettersson, U., Peltonen, L. Nat. Genet. (1996) [Pubmed]
  14. Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity. Eriksson, U., Ricci, R., Hunziker, L., Kurrer, M.O., Oudit, G.Y., Watts, T.H., Sonderegger, I., Bachmaier, K., Kopf, M., Penninger, J.M. Nat. Med. (2003) [Pubmed]
  15. Breast cancer genetics: what we know and what we need. Nathanson, K.L., Wooster, R., Weber, B.L., Nathanson, K.N. Nat. Med. (2001) [Pubmed]
  16. Genetic predisposition to phenytoin-induced birth defects. Strickler, S.M., Dansky, L.V., Miller, M.A., Seni, M.H., Andermann, E., Spielberg, S.P. Lancet (1985) [Pubmed]
  17. A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. Abbas, N., Lücking, C.B., Ricard, S., Dürr, A., Bonifati, V., De Michele, G., Bouley, S., Vaughan, J.R., Gasser, T., Marconi, R., Broussolle, E., Brefel-Courbon, C., Harhangi, B.S., Oostra, B.A., Fabrizio, E., Böhme, G.A., Pradier, L., Wood, N.W., Filla, A., Meco, G., Denefle, P., Agid, Y., Brice, A. Hum. Mol. Genet. (1999) [Pubmed]
  18. Androgen metabolism and prostate cancer: establishing a model of genetic susceptibility. Ross, R.K., Pike, M.C., Coetzee, G.A., Reichardt, J.K., Yu, M.C., Feigelson, H., Stanczyk, F.Z., Kolonel, L.N., Henderson, B.E. Cancer Res. (1998) [Pubmed]
  19. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus. Hein, D.W., Doll, M.A., Gray, K., Rustan, T.D., Ferguson, R.J. Cancer Res. (1993) [Pubmed]
  20. Genetic control of resistance to Listeria monocytogenes: regulation of leukocyte inflammatory responses by the Hc locus. Gervais, F., Stevenson, M., Skamene, E. J. Immunol. (1984) [Pubmed]
  21. Evidence for linkage disequilibrium between HLA-DRB1 gene and multiple sclerosis. The French Research Group on Genetic Susceptibility to MS. Yaouanq, J., Semana, G., Eichenbaum, S., Quelvennec, E., Roth, M.P., Clanet, M., Edan, G., Clerget-Darpoux, F. Science (1997) [Pubmed]
  22. Hypersensitivity to G2 chromatid radiation damage in familial dysplastic naevus syndrome. Sanford, K.K., Tarone, R.E., Parshad, R., Tucker, M.A., Greene, M.H., Jones, G.M. Lancet (1987) [Pubmed]
  23. Histocompatibility antigens in patients with hepatocellular carcinoma and their relationship to chronic hepatitis B virus infection in these patients. Kew, M.C., Gear, A.J., Baumgarten, I., Dusheiko, G.M., Maier, G. Gastroenterology (1979) [Pubmed]
  24. Genetic control of autoimmunity in type 1 diabetes. Todd, J.A. Immunol. Today (1990) [Pubmed]
  25. The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. Pimm, J., McQuillin, A., Thirumalai, S., Lawrence, J., Quested, D., Bass, N., Lamb, G., Moorey, H., Datta, S.R., Kalsi, G., Badacsonyi, A., Kelly, K., Morgan, J., Punukollu, B., Curtis, D., Gurling, H. Am. J. Hum. Genet. (2005) [Pubmed]
  26. T-cell receptor variable genes and genetic susceptibility to celiac disease: an association and linkage study. Roschmann, E., Wienker, T.F., Gerok, W., Volk, B.A. Gastroenterology (1993) [Pubmed]
  27. A functional screen for germ line p53 mutations based on transcriptional activation. Frebourg, T., Barbier, N., Kassel, J., Ng, Y.S., Romero, P., Friend, S.H. Cancer Res. (1992) [Pubmed]
  28. Lymphoid cell surface receptor for Moloney leukemia virus envelope glycoprotein gp71. I. Binding characteristics. Choppin, J., Schaffar-Deshayes, L., Debré, P., Lévy, J.P. J. Immunol. (1981) [Pubmed]
  29. Increased blood pressure and erythrocyte sodium/lithium countertransport activity are not inherited in diabetic nephropathy. Jensen, J.S., Mathiesen, E.R., Nørgaard, K., Hommel, E., Borch-Johnsen, K., Funder, J., Brahm, J., Parving, H.H., Deckert, T. Diabetologia (1990) [Pubmed]
  30. Anti-bovine serum albumin antibodies: genetic heterogeneity and clinical relevance in adult-onset IDDM. Krokowski, M., Caillat-Zucman, S., Timsit, J., Larger, E., Pehuet-Figoni, M., Bach, J.F., Boitard, C. Diabetes Care (1995) [Pubmed]
  31. Allergy and immunology. Smith, D.L., deShazo, R.D. JAMA (1994) [Pubmed]
  32. Mutagen sensitivity in patients with head and neck cancers: a biologic marker for risk of multiple primary malignancies. Schantz, S.P., Spitz, M.R., Hsu, T.C. J. Natl. Cancer Inst. (1990) [Pubmed]
  33. Human lung carcinogen-DNA adduct levels mediated by genetic polymorphisms in vivo. Kato, S., Bowman, E.D., Harrington, A.M., Blomeke, B., Shields, P.G. J. Natl. Cancer Inst. (1995) [Pubmed]
  34. Effect of a diabetic environment in utero on predisposition to type 2 diabetes. Sobngwi, E., Boudou, P., Mauvais-Jarvis, F., Leblanc, H., Velho, G., Vexiau, P., Porcher, R., Hadjadj, S., Pratley, R., Tataranni, P.A., Calvo, F., Gautier, J.F. Lancet (2003) [Pubmed]
  35. Genetic susceptibility to scleroderma-like syndrome induced by vinyl chloride. Black, C.M., Welsh, K.I., Walker, A.E., Bernstein, R.M., Catoggio, L.J., McGregor, A.R., Jones, J.K. Lancet (1983) [Pubmed]
  36. Genetic predisposition to adverse consequences of anti-cholinesterases in 'atypical' BCHE carriers. Loewenstein-Lichtenstein, Y., Schwarz, M., Glick, D., Nørgaard-Pedersen, B., Zakut, H., Soreq, H. Nat. Med. (1995) [Pubmed]
  37. Association of amino acid sequences in the HLA-DQB1 first domain with antitopoisomerase I autoantibody response in scleroderma (progressive systemic sclerosis). Reveille, J.D., Durban, E., MacLeod-St Clair, M.J., Goldstein, R., Moreda, R., Altman, R.D., Arnett, F.C. J. Clin. Invest. (1992) [Pubmed]
  38. Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog. Mahapatra, N.R., O'Connor, D.T., Vaingankar, S.M., Hikim, A.P., Mahata, M., Ray, S., Staite, E., Wu, H., Gu, Y., Dalton, N., Kennedy, B.P., Ziegler, M.G., Ross, J., Mahata, S.K. J. Clin. Invest. (2005) [Pubmed]
  39. SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent. Hassan, Z., Mohan, V., Ali, L., Allotey, R., Barakat, K., Faruque, M.O., Deepa, R., McDermott, M.F., Jackson, A.E., Cassell, P., Curtis, D., Gelding, S.V., Vijayaravaghan, S., Gyr, N., Whitcomb, D.C., Khan, A.K., Hitman, G.A. Am. J. Hum. Genet. (2002) [Pubmed]
  40. Genetic predisposition to phaeochromocytoma: analysis of candidate genes GDNF, RET and VHL. Woodward, E.R., Eng, C., McMahon, R., Voutilainen, R., Affara, N.A., Ponder, B.A., Maher, E.R. Hum. Mol. Genet. (1997) [Pubmed]
  41. Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3. Cheng, Y., Poulos, N.E., Lung, M.L., Hampton, G., Ou, B., Lerman, M.I., Stanbridge, E.J. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  42. Interrelationship of major histocompatibility complex class II alleles and autoantibodies in four ethnic groups with various forms of myositis. Arnett, F.C., Targoff, I.N., Mimori, T., Goldstein, R., Warner, N.B., Reveille, J.D. Arthritis Rheum. (1996) [Pubmed]
  43. Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: a case-control study in an Indian population. Wang, J., Gajalakshmi, V., Jiang, J., Kuriki, K., Suzuki, S., Nagaya, T., Nakamura, S., Akasaka, S., Ishikawa, H., Tokudome, S. Int. J. Cancer (2006) [Pubmed]
  44. Failure of P strain mice to respond to vaccination against schistosomiasis correlates with impaired production of IL-12 and up-regulation of Th2 cytokines that inhibit macrophage activation. Oswald, I.P., Caspar, P., Wynn, T.A., Scharton-Kersten, T., Williams, M.E., Hieny, S., Sher, A., James, S.L. Eur. J. Immunol. (1998) [Pubmed]
  45. Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET. Drzezga, A., Grimmer, T., Riemenschneider, M., Lautenschlager, N., Siebner, H., Alexopoulus, P., Minoshima, S., Schwaiger, M., Kurz, A. J. Nucl. Med. (2005) [Pubmed]
 
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