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MeSH Review

Marek Disease

 
 
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Disease relevance of Marek Disease

 

High impact information on Marek Disease

 

Chemical compound and disease context of Marek Disease

 

Biological context of Marek Disease

 

Anatomical context of Marek Disease

  • An antibody-secreting hybridoma, RPH-6, to Marek's disease tumor-associated surface antigen (MATSA) was produced by somatic-cell hybridization between the mouse myeloma SP2/O-Ag/14 and spleen cells from MSB1 immunized mice [20].
  • The protein encoded by the US3 orthologue of Marek's disease virus is required for efficient de-envelopment of perinuclear virions and involved in actin stress fiber breakdown [21].
  • The pp38 gene of Marek's disease virus (MDV) is necessary for cytolytic infection of B cells and maintenance of the transformed state but not for cytolytic infection of the feather follicle epithelium and horizontal spread of MDV [22].
  • In view of the above, several Marek's disease virus (MDV)-transformed T-cell lines (which grow well in a serum-supplemented medium) were tested for a response to chicken IL-2 when grown in serum-free media [23].
  • Enhancement by interferon of chicken splenocyte natural killer cell activity against Marek's disease tumor cells [24].
 

Gene context of Marek Disease

 

Analytical, diagnostic and therapeutic context of Marek Disease

References

  1. A gene for dihydrofolate reductase in a herpesvirus. Trimble, J.J., Murthy, S.C., Bakker, A., Grassmann, R., Desrosiers, R.C. Science (1988) [Pubmed]
  2. Marek's disease in immunosuppressed chickens: growth of a transplantable lymphoma and development of the disease by natural exposure. Cotter, P.F., Jakowski, R.M., Fredrickson, T.N., Schierman, L.W., McBride, R.A. J. Natl. Cancer Inst. (1975) [Pubmed]
  3. Recombinant fowlpox viruses expressing the glycoprotein B homolog and the pp38 gene of Marek's disease virus. Yanagida, N., Ogawa, R., Li, Y., Lee, L.F., Nazerian, K. J. Virol. (1992) [Pubmed]
  4. Marke's disease herpesviruses. III. Purification and characterization of Marek's disease herpesvirus B antigen. Velicer, L.F., Yager, D.R., Clark, J.L. J. Virol. (1978) [Pubmed]
  5. From essential to beneficial: glycoprotein D loses importance for replication of bovine herpesvirus 1 in cell culture. Schröder, C., Linde, G., Fehler, F., Keil, G.M. J. Virol. (1997) [Pubmed]
  6. Effects of levamisole on pathogenesis of Marek's disease. Kodama, H., Mikami, T., Izawa, H. J. Natl. Cancer Inst. (1980) [Pubmed]
  7. Effect of phosphonoacetate on Marek's disease virus replication. Lee, L.F., Nazerian, K., Leinbach, S.S., Reno, J.M., Boezi, J.A. J. Natl. Cancer Inst. (1976) [Pubmed]
  8. Interaction of MEQ protein and C-terminal-binding protein is critical for induction of lymphomas by Marek's disease virus. Brown, A.C., Baigent, S.J., Smith, L.P., Chattoo, J.P., Petherbridge, L.J., Hawes, P., Allday, M.J., Nair, V. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  9. Growth hormone interacts with the Marek's disease virus SORF2 protein and is associated with disease resistance in chicken. Liu, H.C., Kung, H.J., Fulton, J.E., Morgan, R.W., Cheng, H.H. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  10. Expression of the oncogene of avian reticuloendotheliosis virus in Escherichia coli and identification of the transforming protein in reticuloendotheliosis virus T-transformed cells. Herzog, N.K., Bose, H.R. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  11. Altered cholesteryl ester cycle is associated with lipid accumulation in herpesvirus-infected arterial smooth muscle cells. Hajjar, D.P., Falcone, D.J., Fabricant, C.G., Fabricant, J. J. Biol. Chem. (1985) [Pubmed]
  12. Structure and complete nucleotide sequence of the Marek's disease herpesvirus gp57-65 gene. Coussens, P.M., Velicer, L.F. J. Virol. (1988) [Pubmed]
  13. Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus. Xing, Z., Schat, K.A. J. Virol. (2000) [Pubmed]
  14. Establishment of Marek's disease lymphoblastoid cell lines from transplantable versus primary lymphomas. Calnek, B.W., Murthy, K.K., Schat, K.A. Int. J. Cancer (1978) [Pubmed]
  15. Synthesis and processing of a gp28/32 membrane glycoprotein induced by Marek's disease virus serotype 2. Nakajima, K., Shibayama, T., Kato, S., Kurimura, T., Hirai, K. J. Gen. Virol. (1990) [Pubmed]
  16. Characterization of Marek's disease virus insertion and deletion mutants that lack US1 (ICP22 homolog), US10, and/or US2 and neighboring short-component open reading frames. Parcells, M.S., Anderson, A.S., Cantello, J.L., Morgan, R.W. J. Virol. (1994) [Pubmed]
  17. A repeat sequence, GGGTTA, is shared by DNA of human herpesvirus 6 and Marek's disease virus. Kishi, M., Harada, H., Takahashi, M., Tanaka, A., Hayashi, M., Nonoyama, M., Josephs, S.F., Buchbinder, A., Schachter, F., Ablashi, D.V. J. Virol. (1988) [Pubmed]
  18. The glycoprotein D (US6) homolog is not essential for oncogenicity or horizontal transmission of Marek's disease virus. Anderson, A.S., Parcells, M.S., Morgan, R.W. J. Virol. (1998) [Pubmed]
  19. Reconstitution of Marek's disease virus serotype 1 (MDV-1) from DNA cloned as a bacterial artificial chromosome and characterization of a glycoprotein B-negative MDV-1 mutant. Schumacher, D., Tischer, B.K., Fuchs, W., Osterrieder, N. J. Virol. (2000) [Pubmed]
  20. A monoclonal antibody reactive with Marek's disease tumor-associated surface antigen. Lee, L.F., Liu, X., Sharma, J.M., Nazerian, K., Bacon, L.D. J. Immunol. (1983) [Pubmed]
  21. The protein encoded by the US3 orthologue of Marek's disease virus is required for efficient de-envelopment of perinuclear virions and involved in actin stress fiber breakdown. Schumacher, D., Tischer, B.K., Trapp, S., Osterrieder, N. J. Virol. (2005) [Pubmed]
  22. The pp38 gene of Marek's disease virus (MDV) is necessary for cytolytic infection of B cells and maintenance of the transformed state but not for cytolytic infection of the feather follicle epithelium and horizontal spread of MDV. Gimeno, I.M., Witter, R.L., Hunt, H.D., Reddy, S.M., Lee, L.F., Silva, R.F. J. Virol. (2005) [Pubmed]
  23. Marek's disease virus-transformed chicken T-cell lines respond to lymphokines. Kaplan, M.H., Dhar, A., Brown, T.R., Sundick, R.S. Vet. Immunol. Immunopathol. (1992) [Pubmed]
  24. Enhancement by interferon of chicken splenocyte natural killer cell activity against Marek's disease tumor cells. Ding, A.H., Lam, K.M. Vet. Immunol. Immunopathol. (1986) [Pubmed]
  25. The RNA subunit of telomerase is encoded by Marek's disease virus. Fragnet, L., Blasco, M.A., Klapper, W., Rasschaert, D. J. Virol. (2003) [Pubmed]
  26. Identification and transcriptional analysis of the homologues of the herpes simplex virus type 1 UL30 to UL40 genes in the genome of nononcogenic Marek's disease virus serotype 2. Izumiya, Y., Jang, H.K., Sugawara, M., Ikeda, Y., Miura, R., Nishimura, Y., Nakamura, K., Miyazawa, T., Kai, C., Mikami, T. J. Gen. Virol. (1999) [Pubmed]
  27. Identification and transcriptional analysis of the homologues of the herpes simplex virus type 1 UL41 to UL51 genes in the genome of nononcogenic Marek's disease virus serotype 2. Izumiya, Y., Jang, H.K., Kashiwase, H., Cai, J.S., Nishimura, Y., Tsushima, Y., Kato, K., Miyazawa, T., Kai, C., Mikami, T. J. Gen. Virol. (1998) [Pubmed]
  28. Marek's disease virus (MDV) homologues of herpes simplex virus type 1 UL49 (VP22) and UL48 (VP16) genes: high-level expression and characterization of MDV-1 VP22 and VP16. Dorange, F., El Mehdaoui, S., Pichon, C., Coursaget, P., Vautherot, J.F. J. Gen. Virol. (2000) [Pubmed]
  29. Identification and characterization of Marek's disease virus serotype 1 (MDV1) ICP22 gene product: MDV1 ICP22 transactivates the MDV1 ICP27 promoter synergistically with MDV1 ICP4. Kato, K., Izumiya, Y., Tohya, Y., Takahashi, E., Hirai, K., Kawaguchi, Y. Vet. Microbiol. (2002) [Pubmed]
  30. Transcriptional analysis of Marek's disease virus glycoprotein D, I, and E genes: gD expression is undetectable in cell culture. Tan, X., Brunovskis, P., Velicer, L.F. J. Virol. (2001) [Pubmed]
  31. Synthesis and processing of the Marek's disease herpesvirus B antigen glycoprotein complex. Sithole, I., Lee, L.F., Velicer, L.F. J. Virol. (1988) [Pubmed]
  32. Antigen A gene of Marek's disease virus (MDV) detects two mRNA species (3.7 and 2.1 kb) in MDV- and HVT-infected cells. Maray, T., Levy, H., Malkinson, M., Becker, Y. Virus Genes (1988) [Pubmed]
  33. Circular forms of viral DNA in Marek's disease virus-transformed lymphoblastoid cells. Rziha, H.J., Bauer, B. Arch. Virol. (1982) [Pubmed]
  34. Detection of contamination of vaccines with the reticuloendotheliosis virus by reverse transcriptase polymerase chain reaction (RT-PCR). Takagi, M., Ishikawa, K., Nagai, H., Sasaki, T., Gotoh, K., Koyama, H. Virus Res. (1996) [Pubmed]
 
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