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MeSH Review

Polypodiaceae

 
 
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Disease relevance of Polypodiaceae

 

High impact information on Polypodiaceae

 

Anatomical context of Polypodiaceae

  • Through tissue culture and isotope tracing, it was found that Gusuibu (Drynaria baronii) injection (GI) significantly promoted calcification of the cultivated chick embryo bone primordium (CEBP), increased ALP activity in the cultivated tissue, and accelerated synthesis of proteoglycan [8].
 

Associations of Polypodiaceae with chemical compounds

  • (Polypodiaceae) two diterpenes, entkaurane-2 beta, 16 alpha-diol and ent-kaur-16-ene-2 beta, 15 alpha-diol, were isolated by repeated column chromatography using silica gel and silica gel impregnated with silver nitrate [9].
  • Among these active herbs, the methanol extract from the rhizomes of Drynaria fortunei showed the most potent proliferative activity, and the cell proliferations were significantly increase by 136 and 158% in the MCF-7 and ROS 17/2.8 cells, respectively, when treated with 100 microg/mL [10].
 

Gene context of Polypodiaceae

  • Similarly, treatment of osteoclasts-containing long bone cells with Drynariae Rhizoma (DR) extracts prevented the intracellular maturation of Cat K, suggesting that DR may disrupt the intracellular trafficking of pro Cat K [11].

References

  1. Inhibitory activity of Drynariae rhizoma extracts on cathepsin having bone resorption activity. Jeong, J.C., Yoon, C.H., Jeong, C.W., Lee, Y.C., Chang, Y.C., Kim, C.H. Immunopharmacology and immunotoxicology. (2004) [Pubmed]
  2. Flavonoid of Drynaria fortunei protects against acute renal failure. Long, M., Qiu, D., Li, F., Johnson, F., Luft, B. Phytotherapy research : PTR. (2005) [Pubmed]
  3. Immobilization of Chinese herbal medicine onto the surface-modified calcium hydrogenphosphate. Lin, F.H., Dong, G.C., Chen, K.S., Jiang, G.J., Huang, C.W., Sun, J.S. Biomaterials (2003) [Pubmed]
  4. The effect of Gu-Sui-Bu (Drynaria fortunei J. Sm) immobilized modified calcium hydrogenphosphate on bone cell activities. Sun, J.S., Dong, G.C., Lin, C.Y., Sheu, S.Y., Lin, F.H., Chen, L.T., Chang, W.H., Wang, Y.J. Biomaterials (2003) [Pubmed]
  5. Detection and partial sequence of phytochrome genes in the ferns Anemia phyllitidis (L.)Sw (Schizaeaceae) and Dryopteris filix-mas L. (Polypodiaceae) by using polymerase-chain reaction technology. Maucher, H.P., Scheuerlein, R., Schraudolf, H. Photochem. Photobiol. (1992) [Pubmed]
  6. Flavanoid of Drynaria fortunei protects against gentamicin ototoxicity. Long, M., Smouha, E.E., Qiu, D., Li, F., Johnson, F., Luft, B. Phytotherapy research : PTR. (2004) [Pubmed]
  7. Drynariae Rhizoma promotes osteoblast differentiation and mineralization in MC3T3-E1 cells through regulation of bone morphogenetic protein-2, alkaline phosphatase, type I collagen and collagenase-1. Jeong, J.C., Lee, J.W., Yoon, C.H., Kim, H.M., Kim, C.H. Toxicology in vitro : an international journal published in association with BIBRA. (2004) [Pubmed]
  8. Stimulative effects of gusuibu (Drynaria baronii) injection on chick embryo bone primordium calcification in vitro. Ma, K.C., Zhu, T.Y., Wang, F.X. Am. J. Chin. Med. (1996) [Pubmed]
  9. Isolation of two cytotoxic diterpenes from the fern Pteris multifida. Woerdenbag, H.J., Lutke, L.R., Bos, R., Stevens, J.F., Hulst, R., Kruizinga, W.H., Zhu, Y.P., Elema, E.T., Hendriks, H., van Uden, W., Pras, N. Z. Naturforsch., C, J. Biosci. (1996) [Pubmed]
  10. Proliferative effects of flavan-3-ols and propelargonidins from rhizomes of Drynaria fortunei on MCF-7 and osteoblastic cells. Chang, E.J., Lee, W.J., Cho, S.H., Choi, S.W. Arch. Pharm. Res. (2003) [Pubmed]
  11. Inhibition of Drynariae Rhizoma extracts on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts. Jeong, J.C., Kang, S.K., Youn, C.H., Jeong, C.W., Kim, H.M., Lee, Y.C., Chang, Y.C., Kim, C.H. Int. Immunopharmacol. (2003) [Pubmed]
 
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