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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Genetic Determinism

 
 
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High impact information on Genetic Determinism

  • These observations demonstrate that type I hyperprolinemia is present in a subset of schizophrenic patients, and suggest that the genetic determinism of type I hyperprolinemia is complex, the severity of hyperprolinemia depending on the nature and number of hits affecting the PRODH locus [1].
  • This new marker provides a valuable tool to assess the risk for putative bradykinin-associated disorders with genetic determinism [2].
  • The direct connection between the dilated cardiomyopathy and the HLA DQA1 gene confirms the hypothesis on the genetic determinism of this disease [3].

References

  1. PRODH mutations and hyperprolinemia in a subset of schizophrenic patients. Jacquet, H., Raux, G., Thibaut, F., Hecketsweiler, B., Houy, E., Demilly, C., Haouzir, S., Allio, G., Fouldrin, G., Drouin, V., Bou, J., Petit, M., Campion, D., Frébourg, T. Hum. Mol. Genet. (2002) [Pubmed]
  2. A novel sequence polymorphism in the promoter region of the human B2-bradykinin receptor gene. Braun, A., Maier, E., Kammerer, S., Müller, B., Roscher, A.A. Hum. Genet. (1996) [Pubmed]
  3. Immunogenetic risk factors of dilated cardiomyopathy. Popovici, M., Groppa, L., Kalinina, L. Blood pressure. Supplement. (1996) [Pubmed]
 
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