Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Genes, Y-Linked

Keitges, E.A. et al., Chang, B.H. et al., Simpson, E. et al., Odorisio, T. et al., Keitges, E. et al.

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High impact information on Genes, Y-Linked

X-linkage of steroid sulphatase in the mouse is evidence for a functional Y-linked allele [1].
It is of interest that in mouse a Y-linked gene controlling spermatogenesis (Spy) maps near Hya on the Sxr fragment: they could be the same or closely linked genes [2].
Ube1y is a Y-linked gene transcribed in the testis, which maps to a region of the mouse Y required for normal spermatogonial proliferation [3].
From the intron sequences of the Ube 1 genes, we calculated the divergence of the Y-linked genes (Y = 0.161) and that of the X-linked genes (X = 0.107) between mouse and rat, and found the Y/X ratio to be 1.50 [4].
Dosage studies and the inheritance pattern of the gene for steroid sulfatase (Sts) in the mouse have previously provided indirect evidence for a functional Y-linked allele which recombines obligatorily with its X-linked allele in male meiosis [5].

References

X-linkage of steroid sulphatase in the mouse is evidence for a functional Y-linked allele. Keitges, E., Rivest, M., Siniscalco, M., Gartler, S.M. Nature (1985) [Pubmed]
Mapping the H-Y gene. Simpson, E., Chandler, P., McLaren, A., Goulmy, E., Disteche, C.M., Page, D.C., Ferguson-Smith, M.A. Development (1987) [Pubmed]
Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes. Odorisio, T., Mahadevaiah, S.K., McCarrey, J.R., Burgoyne, P.S. Dev. Biol. (1996) [Pubmed]
Estimating the intensity of male-driven evolution in rodents by using X-linked and Y-linked Ube 1 genes and pseudogenes. Chang, B.H., Li, W.H. J. Mol. Evol. (1995) [Pubmed]
Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse. Keitges, E.A., Schorderet, D.F., Gartler, S.M. Genetics (1987) [Pubmed]

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Genes, Y-Linked

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