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MeSH Review

Membrane Fusion

 
 
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Disease relevance of Membrane Fusion

 

High impact information on Membrane Fusion

  • Despite reports suggesting a potential role in membrane fusion, the V(0) subunit of the (+)H/ATPase has remained an unlikely candidate for the fusion pore [6].
  • Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome [7].
  • VCP is associated with a variety of cellular activities, including cell cycle control, membrane fusion and the ubiquitin-proteasome degradation pathway [8].
  • VPS33B encodes a homolog of the class C yeast vacuolar protein sorting gene, Vps33, that contains a Sec1-like domain important in the regulation of vesicle-to-target SNARE complex formation and subsequent membrane fusion [7].
  • Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13 [9].
 

Chemical compound and disease context of Membrane Fusion

 

Biological context of Membrane Fusion

 

Anatomical context of Membrane Fusion

 

Associations of Membrane Fusion with chemical compounds

 

Gene context of Membrane Fusion

 

Analytical, diagnostic and therapeutic context of Membrane Fusion

References

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