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MeSH Review

Enzyme-Linked Immunosorbent Assay

 
 
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Disease relevance of Enzyme-Linked Immunosorbent Assay

 

Psychiatry related information on Enzyme-Linked Immunosorbent Assay

  • Amyloid-beta (Abeta) peptide levels are widely measured by enzyme-linked immunosorbent assay (ELISA) in Alzheimer's disease research [6].
  • Sera from mice treated with purified anti-idiotypic antibodies (anti-Id) were found to contain inhibitory activity in an ELISA specific for the 14-4-4S Id, whereas sera from control mice treated with heterologous normal Ig did not [7].
  • Specificity for PrP is confirmed by a sandwich enzyme-linked immunosorbent assay utilizing V5B2, which discriminates between CJD and normal samples without proteinase K treatment, and by immunoprecipitation from CJD brain homogenate [8].
  • This study shows that the current ELISA test for CSF tau is not sensitive and specific enough to distinguish early AD from other dementias and indicates that in the interpretation of CSF tau analysis as a diagnostic tool, the apoE genotype should also be taken into account [9].
  • In a study of Preventive Medicine and Education Program, fibrinogen (clotting method) and factor VIIag (ELISA), in addition to other metabolic parameters, life-style and familial history, were investigated in 451 students (313 females and 138 males, age 15-17 years) from two high schools of Florence [10].
 

High impact information on Enzyme-Linked Immunosorbent Assay

 

Chemical compound and disease context of Enzyme-Linked Immunosorbent Assay

 

Biological context of Enzyme-Linked Immunosorbent Assay

 

Anatomical context of Enzyme-Linked Immunosorbent Assay

 

Associations of Enzyme-Linked Immunosorbent Assay with chemical compounds

  • By the ELISA, MOMP-liposomes, but not plain liposomes lacking MOMP, avidly fix C3 [31].
  • To further confirm the presence of antihyaluronate antibodies, hyaluronidase-digested streptococcal hyaluronate was conjugated to biotin and used as an antigen in the ELISA [32].
  • Inhibition studies using an ELISA demonstrated that heparan sulfate was a major antigenic determinant [33].
  • Conditioned media samples prepared with cells from these mice, on day 2 after infection, produced 11-43 pg/million cells of IFN-gamma and 12-19 pg/million cells of TNF as evaluated by specific protein enzyme-linked immunosorbent assays [34].
  • Acid/ethanol extracts of human PMNs assayed by ELISA contained an average of 355 ng of TGF/beta 1 per 10(9) cells potentially available for secretion during degranulation of PMNs [35].
 

Gene context of Enzyme-Linked Immunosorbent Assay

  • MAIN OUTCOME MEASURES--Supernatants from trophoblast-activated peripheral blood mononuclear cells from all participants were tested for toxic effects on mouse embryos and by enzyme-linked immunosorbent assay (ELISA) for interferon gamma (IFN-gamma) [36].
  • Assembly of an extracellular fibronectin matrix by VHL-/- renal carcinoma cells, as determined by immunofluorescence and ELISA assays, was grossly defective compared with VHL+/+ renal carcinoma cells [37].
  • In addition, IL-2 was not detected (less than 50 pg/ml) in 16 joint samples using an ELISA [38].
  • Plasma samples (n = 454) were collected three times/week from all patients (n = 25) undergoing renal transplantation during a 9-month consecutive period, and assayed by ELISA and functional assays for TNF, PC, and free PS (FPS) [39].
  • Amyloid A fibrils in spleen homogenates were denatured by formic acid and AA protein was quantified by ELISA using anti-mouse apoSAA antibodies [40].
 

Analytical, diagnostic and therapeutic context of Enzyme-Linked Immunosorbent Assay

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