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MeSH Review

Synovial Fluid

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Disease relevance of Synovial Fluid


Psychiatry related information on Synovial Fluid


High impact information on Synovial Fluid


Chemical compound and disease context of Synovial Fluid


Biological context of Synovial Fluid


Anatomical context of Synovial Fluid


Associations of Synovial Fluid with chemical compounds


Gene context of Synovial Fluid


Analytical, diagnostic and therapeutic context of Synovial Fluid


  1. Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia. Ruprecht, C.R., Gattorno, M., Ferlito, F., Gregorio, A., Martini, A., Lanzavecchia, A., Sallusto, F. J. Exp. Med. (2005) [Pubmed]
  2. Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis. Guerne, P.A., Zuraw, B.L., Vaughan, J.H., Carson, D.A., Lotz, M. J. Clin. Invest. (1989) [Pubmed]
  3. C3b inactivator in the rheumatic diseases. Measurement by radial immunodiffusion and by inhibition of formation of properdin pathway C3 convertase. Whaley, K., Schur, P.H., Ruddy, S. J. Clin. Invest. (1976) [Pubmed]
  4. Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis. Koch, A.E., Kunkel, S.L., Harlow, L.A., Johnson, B., Evanoff, H.L., Haines, G.K., Burdick, M.D., Pope, R.M., Strieter, R.M. J. Clin. Invest. (1992) [Pubmed]
  5. Elevated levels of antibodies to Epstein-Barr virus antigens in sera and synovial fluids of patients with rheumatoid arthritis. Alspaugh, M.A., Henle, G., Lennette, E.T., Henle, W. J. Clin. Invest. (1981) [Pubmed]
  6. Synovial leukocytosis in infectious arthritis. McCutchan, H.J., Fisher, R.C. Clin. Orthop. Relat. Res. (1990) [Pubmed]
  7. Synovial-fluid beta 2-microglobulin levels in dialysis arthropathy. Sethi, D., Gower, P.E. N. Engl. J. Med. (1986) [Pubmed]
  8. The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis. McInnes, I.B., al-Mughales, J., Field, M., Leung, B.P., Huang, F.P., Dixon, R., Sturrock, R.D., Wilkinson, P.C., Liew, F.Y. Nat. Med. (1996) [Pubmed]
  9. Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 A resolution. Wery, J.P., Schevitz, R.W., Clawson, D.K., Bobbitt, J.L., Dow, E.R., Gamboa, G., Goodson, T., Hermann, R.B., Kramer, R.M., McClure, D.B. Nature (1991) [Pubmed]
  10. Corticosteroids inhibit prostaglandin production by rheumatiod synovia. Kantrowitz, F., Robinson, D.R., McGuire, M.B., Levine, L. Nature (1975) [Pubmed]
  11. Evidence for the effects of a superantigen in rheumatoid arthritis. Paliard, X., West, S.G., Lafferty, J.A., Clements, J.R., Kappler, J.W., Marrack, P., Kotzin, B.L. Science (1991) [Pubmed]
  12. Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis. Robinson, D.R., Tashjian, A.H., Levine, L. J. Clin. Invest. (1975) [Pubmed]
  13. Salmonella lipopolysaccharide in synovial cells from patients with reactive arthritis. Granfors, K., Jalkanen, S., Lindberg, A.A., Mäki-Ikola, O., von Essen, R., Lahesmaa-Rantala, R., Isomäki, H., Saario, R., Arnold, W.J., Toivanen, A. Lancet (1990) [Pubmed]
  14. Calcium oxalate microcrystalline-associated arthritis in end-stage renal disease. Hoffman, G.S., Schumacher, H.R., Paul, H., Cherian, V., Reed, R., Ramsay, A.G., Franck, W.A. Ann. Intern. Med. (1982) [Pubmed]
  15. Inorganic pyrophosphate in metabolic diseases predisposing to calcium pyrophosphate dihydrate crystal deposition. Doherty, M., Chuck, A., Hosking, D., Hamilton, E. Arthritis Rheum. (1991) [Pubmed]
  16. Identification of cartilage matrix glycoprotein in synovial fluid in human osteoarthritis. Fife, R.S. Arthritis Rheum. (1988) [Pubmed]
  17. Beta 1 integrin-mediated interaction with extracellular matrix proteins regulates cytokine gene expression in synovial fluid cells of rheumatoid arthritis patients. Miyake, S., Yagita, H., Maruyama, T., Hashimoto, H., Miyasaka, N., Okumura, K. J. Exp. Med. (1993) [Pubmed]
  18. Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis. Zvaifler, N.J., Steinman, R.M., Kaplan, G., Lau, L.L., Rivelis, M. J. Clin. Invest. (1985) [Pubmed]
  19. Carbohydrate heterogeneity of fibronectins. Synovial fluid fibronectin resembles the form secreted by cultured synoviocytes but differs from the plasma form. Carsons, S., Lavietes, B.B., Slomiany, A., Diamond, H.S., Berkowitz, E. J. Clin. Invest. (1987) [Pubmed]
  20. Stimulation of suppressive T cell responses by human but not bacterial 60-kD heat-shock protein in synovial fluid of patients with rheumatoid arthritis. van Roon, J.A., van Eden, W., van Roy, J.L., Lafeber, F.J., Bijlsma, J.W. J. Clin. Invest. (1997) [Pubmed]
  21. Clonal heterogeneity of synovial fluid T lymphocytes from patients with rheumatoid arthritis. Duby, A.D., Sinclair, A.K., Osborne-Lawrence, S.L., Zeldes, W., Kan, L., Fox, D.A. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  22. Human neutrophils produce high levels of the interleukin 1 receptor antagonist in response to granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha. McColl, S.R., Paquin, R., Ménard, C., Beaulieu, A.D. J. Exp. Med. (1992) [Pubmed]
  23. Activation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon gamma. Sengupta, T.K., Chen, A., Zhong, Z., Darnell, J.E., Ivashkiv, L.B. J. Exp. Med. (1995) [Pubmed]
  24. Arthritogenic monoclonal antibodies from K/BxN mice. Maccioni, M., Zeder-Lutz, G., Huang, H., Ebel, C., Gerber, P., Hergueux, J., Marchal, P., Duchatelle, V., Degott, C., van Regenmortel, M., Benoist, C., Mathis, D. J. Exp. Med. (2002) [Pubmed]
  25. Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies. Lotz, M., Tsoukas, C.D., Robinson, C.A., Dinarello, C.A., Carson, D.A., Vaughan, J.H. J. Clin. Invest. (1986) [Pubmed]
  26. Urate spherulites in gouty synovia. Fiechtner, J.J., Simkin, P.A. JAMA (1981) [Pubmed]
  27. Synovial fluid glucose. Owen, D.S. JAMA (1978) [Pubmed]
  28. The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. Sandy, J.D., Flannery, C.R., Neame, P.J., Lohmander, L.S. J. Clin. Invest. (1992) [Pubmed]
  29. Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue. Fava, R.A., Olsen, N.J., Spencer-Green, G., Yeo, K.T., Yeo, T.K., Berse, B., Jackman, R.W., Senger, D.R., Dvorak, H.F., Brown, L.F. J. Exp. Med. (1994) [Pubmed]
  30. Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis. Koch, A.E., Kunkel, S.L., Harlow, L.A., Mazarakis, D.D., Haines, G.K., Burdick, M.D., Pope, R.M., Walz, A., Strieter, R.M. J. Clin. Invest. (1994) [Pubmed]
  31. A mutation in a CD44 variant of inflammatory cells enhances the mitogenic interaction of FGF with its receptor. Nedvetzki, S., Golan, I., Assayag, N., Gonen, E., Caspi, D., Gladnikoff, M., Yayon, A., Naor, D. J. Clin. Invest. (2003) [Pubmed]
  32. Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis. Klickstein, L.B., Shapleigh, C., Goetzl, E.J. J. Clin. Invest. (1980) [Pubmed]
  33. Self-perpetuating mechanisms of immunoglobulin G aggregation in rheumatoid inflammation. Lunec, J., Blake, D.R., McCleary, S.J., Brailsford, S., Bacon, P.A. J. Clin. Invest. (1985) [Pubmed]
  34. Studies with human leukocyte lysosomes. Evidence for antilysosome antibodies in lupus erythematosus and for the presence of lysosomal antigen in inflammatory diseases. Bell, D.A., Thiem, P.A., Vaughan, J.H., Leddy, J.P. J. Clin. Invest. (1975) [Pubmed]
  35. Balance of synovial fluid IL-1 beta and IL-1 receptor antagonist and recovery from Lyme arthritis. Miller, L.C., Lynch, E.A., Isa, S., Logan, J.W., Dinarello, C.A., Steere, A.C. Lancet (1993) [Pubmed]
  36. Biologically active thrombomodulin is synthesized by adherent synovial fluid cells and is elevated in synovial fluid of patients with rheumatoid arthritis. Conway, E.M., Nowakowski, B. Blood (1993) [Pubmed]
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