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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Life Change Events

 
 
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Disease relevance of Life Change Events

 

Psychiatry related information on Life Change Events

 

High impact information on Life Change Events

 

Chemical compound and disease context of Life Change Events

 

Biological context of Life Change Events

  • Effects were assessed by measuring salivary cortisol production at baseline and in response to two potentially stressful events, a heel-stick blood draw and a physical exam, in infants born at 33-34 weeks gestation [20].
  • It is concluded that the delayed response to formalin injection is the result of complex interactions involving peripheral mechanisms and central neuronal plasticity in which activity initiated by a noxious input persists after the cessation of the input as a consequence of a stressful event such as the cold-water swim [21].
  • This is consistent with the idea that birds breeding in extreme environments with short breeding seasons may exhibit a decreased adrenocortical response to stressful events to prevent high corticosterone concentrations from inducing interruptions of reproductive behavior [22].
  • In response to a stressful event, the stimulation of the corticotropin-releasing hormone (CRH) system is probably involved in the observed modifications of body temperature and colonic motility [23].
  • The data now available indicate that labour and lactation, or the occurrence of a stressful event such as the very first jump with a parachute causes in NGF plasma levels as well as changes in the distribution of NGF receptors on lymphocytes [24].
 

Anatomical context of Life Change Events

 

Gene context of Life Change Events

  • We hypothesized that CRF might mediate some of the effects of cocaine and as such it may be a link between stressful events and increased vulnerability to cocaine addiction [30].
  • Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event [25].
  • We conclude that the interaction between CRH and MR presents a novel mechanism involved in the adaptation of the brain to psychologically stressful events [31].
  • OBJECTIVES: The objective was to examine the prevalence of psychological distress in patients hospitalized for an acute exacerbation COPD, assess how they appraise and cope with the recent stressful event, and examine the relationships among coping, appraisal, and psychological distress [32].
  • INTERVENTION: Patients were assigned to write either about the most stressful event of their lives (n = 71; 39 asthma, 32 rheumatoid arthritis) or about emotionally neutral topics (n = 41; 22 asthma, 19 rheumatoid arthritis) (the control intervention) [12].
 

Analytical, diagnostic and therapeutic context of Life Change Events

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