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MeSH Review

Cryptosporidium

 
 
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Disease relevance of Cryptosporidium

 

High impact information on Cryptosporidium

 

Chemical compound and disease context of Cryptosporidium

 

Biological context of Cryptosporidium

 

Anatomical context of Cryptosporidium

 

Associations of Cryptosporidium with chemical compounds

 

Gene context of Cryptosporidium

  • In this study, we characterized the single-stranded DNA binding features of two distinct types (i.e. short and long) of RPA1 subunits from Cryptosporidium parvum (CpRPA1A and CpRPA1B) [29].
  • Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42 [30].
  • Interleukin-4 and transforming growth factor beta have opposing regulatory effects on gamma interferon-mediated inhibition of Cryptosporidium parvum reproduction [31].
  • An increase in mRNA levels for TNF and Tnfrsf1 in the bile ducts of Tnfsf5-/-(CD40 ligand or CD154 knockout) mice developing cholangitis following infection by Cryptosporidium parvum (CP) is accompanied by staining for TNFalpha in areas of inflammation [32].
  • Absence of weight loss during Cryptosporidium infection in susceptible mice deficient in Fas-mediated apoptosis [33].
 

Analytical, diagnostic and therapeutic context of Cryptosporidium

References

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  19. Protective monoclonal antibody defines a circumsporozoite-like glycoprotein exoantigen of Cryptosporidium parvum sporozoites and merozoites. Riggs, M.W., Stone, A.L., Yount, P.A., Langer, R.C., Arrowood, M.J., Bentley, D.L. J. Immunol. (1997) [Pubmed]
  20. Calcium regulation in protozoan parasites. Moreno, S.N., Docampo, R. Curr. Opin. Microbiol. (2003) [Pubmed]
  21. Intact intestinal mRNAs and intestinal epithelial cell esterase, but not Cryptosporidium parvum, reach mesenteric lymph nodes of infected mice. Ponnuraj, E.M., Hayward, A.R. J. Immunol. (2001) [Pubmed]
  22. Chemoprophylaxis of Cryptosporidium parvum infection with paromomycin in kids and immunological study. Mancassola, R., Reperant, J.M., Naciri, M., Chartier, C. Antimicrob. Agents Chemother. (1995) [Pubmed]
  23. Human intestinal epithelial cells respond to Cryptosporidium parvum infection with increased prostaglandin H synthase 2 expression and prostaglandin E2 and F2alpha production. Laurent, F., Kagnoff, M.F., Savidge, T.C., Naciri, M., Eckmann, L. Infect. Immun. (1998) [Pubmed]
  24. Kinetic characterization of bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) from Cryptosporidium hominis: a paradigm shift for ts activity and channeling behavior. Atreya, C.E., Anderson, K.S. J. Biol. Chem. (2004) [Pubmed]
  25. Tumour necrosis factor alpha changes porcine intestinal ion transport through a paracrine mechanism involving prostaglandins. Kandil, H.M., Berschneider, H.M., Argenzio, R.A. Gut (1994) [Pubmed]
  26. Vapreotide, a somatostatin analogue, in cryptosporidiosis and other AIDS-related diarrhoeal diseases. Girard, P.M., Goldschmidt, E., Vittecoq, D., Massip, P., Gastiaburu, J., Meyohas, M.C., Coulaud, J.P., Schally, A.V. AIDS (1992) [Pubmed]
  27. Synthetic DNA minor groove-binding drugs. Reddy, B.S., Sondhi, S.M., Lown, J.W. Pharmacol. Ther. (1999) [Pubmed]
  28. Efficacy of nitazoxanide against Cryptosporidium parvum in cell culture and in animal models. Theodos, C.M., Griffiths, J.K., D'Onfro, J., Fairfield, A., Tzipori, S. Antimicrob. Agents Chemother. (1998) [Pubmed]
  29. The protozoan parasite Cryptosporidium parvum possesses two functionally and evolutionarily divergent replication protein A large subunits. Rider, S.D., Cai, X., Sullivan, W.J., Smith, A.T., Radke, J., White, M., Zhu, G. J. Biol. Chem. (2005) [Pubmed]
  30. Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42. Chen, X.M., Splinter, P.L., Tietz, P.S., Huang, B.Q., Billadeau, D.D., LaRusso, N.F. J. Biol. Chem. (2004) [Pubmed]
  31. Interleukin-4 and transforming growth factor beta have opposing regulatory effects on gamma interferon-mediated inhibition of Cryptosporidium parvum reproduction. Lean, I.S., McDonald, S.A., Bajaj-Elliott, M., Pollok, R.C., Farthing, M.J., McDonald, V. Infect. Immun. (2003) [Pubmed]
  32. Requirement for TNF-Tnfrsf1 signalling for sclerosing cholangitis in mice chronically infected by Cryptosporidium parvum. Ponnuraj, E.M., Hayward, A.R. Clin. Exp. Immunol. (2002) [Pubmed]
  33. Absence of weight loss during Cryptosporidium infection in susceptible mice deficient in Fas-mediated apoptosis. Motta, I., Gissot, M., Kanellopoulos, J.M., Ojcius, D.M. Microbes Infect. (2002) [Pubmed]
  34. Nested polymerase chain reaction for amplification of the Cryptosporidium oocyst wall protein gene. Pedraza-Díaz, S., Amar, C., Nichols, G.L., McLauchlin, J. Emerging Infect. Dis. (2001) [Pubmed]
  35. Activity of buforin II alone and in combination with azithromycin and minocycline against Cryptosporidium parvum in cell culture. Giacometti, A., Cirioni, O., Del Prete MS, n.u.l.l., Barchiesi, F., Fineo, A., Scalise, G. J. Antimicrob. Chemother. (2001) [Pubmed]
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  37. Effects of Cryptosporidium parvum infection in Peruvian children: growth faltering and subsequent catch-up growth. Checkley, W., Epstein, L.D., Gilman, R.H., Black, R.E., Cabrera, L., Sterling, C.R. Am. J. Epidemiol. (1998) [Pubmed]
 
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