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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

G2 Phase

 
 
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Disease relevance of G2 Phase

 

High impact information on G2 Phase

 

Chemical compound and disease context of G2 Phase

 

Biological context of G2 Phase

 

Anatomical context of G2 Phase

 

Associations of G2 Phase with chemical compounds

 

Gene context of G2 Phase

  • The Cul4-containing E3 is active during ongoing replication, while SCF-Skp2 operates both in S and G2 phases [29].
  • Rad51-deficient cells arrested in G2 phase and formed supernumerary functional centrosomes, as assessed by light and serial section electron microscopy [19].
  • Synchronized cultures confirm that CYCD3;1-expressing (but not CYCD2;1-expressing) cells show increased G2-phase length and delayed activation of mitotic genes such as B-type cyclins, suggesting that CYCD3;1 has a specific G1/S role [30].
  • In a screen designed to isolate human cDNAs that complement a yeast G2 phase checkpoint mutation (mec1), we isolated a cDNA homologous to the Saccharomyces cerevisiae CDC34 gene [31].
  • To provide a link between p-FADD and NF-kappaB, cell culture studies demonstrated that overexpression of p-FADD leads to an increase in NF-kappaB activity and a decrease in the number of cells in the G2 phase of the cell cycle, compared with cells expressing the nonphosphorylatable form of FADD or the vector control [32].
 

Analytical, diagnostic and therapeutic context of G2 Phase

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