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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Outpatients


Psychiatry related information on Outpatients


High impact information on Outpatients

  • METHODS: We randomly assigned 681 adults with a chronic nonpsychotic major depressive disorder to 12 weeks of outpatient treatment with nefazodone (maximal dose, 600 mg per day), the cognitive behavioral-analysis system of psychotherapy (16 to 20 sessions), or both [11].
  • Outpatient parenteral antimicrobial-drug therapy [12].
  • CONCLUSIONS: In Finland, after nationwide reductions in the use of macrolide antibiotics for outpatient therapy, there was a significant decline in the frequency of erythromycin resistance among group A streptococci isolated from throat swabs and pus samples [13].
  • The study design allowed outpatients taking low-molecular-weight heparin to go home immediately and hospitalized patients taking low-molecular-weight heparin to be discharged early [14].
  • Fluoxetine may be most appropriate for patients with moderate depression who can be treated as outpatients [15].

Chemical compound and disease context of Outpatients


Biological context of Outpatients


Anatomical context of Outpatients


Associations of Outpatients with chemical compounds


Gene context of Outpatients

  • CLL cells were identified by 4-color flow cytometric analysis of CD19/CD5/CD79b/CD20 expression in 910 outpatients over 40 years old [35].
  • CONCLUSION: IL-2 and IFN-alpha-2A is well tolerated in the outpatient treatment setting and demonstrates significant clinical activity against RCCa [36].
  • METHODS: Caucasian patients with RA and control subjects were recruited from a faculty outpatient practice [37].
  • Seventy-five NIDDM patients attending the outpatient clinic of the Department of Internal Medicine of the University Hospital in Padua, Italy participated in the cross-sectional part of our study [38].
  • METHODS: Deoxyribonucleic (DNA) samples obtained from 389 HCM outpatients seen at this tertiary referral center were analyzed for mutations, using polymerase chain reaction, denaturing high-performance liquid chromatography, and DNA sequencing for all 38 protein-coding exons of MYH7 [39].

Analytical, diagnostic and therapeutic context of Outpatients


  1. Heart failure in outpatients: a randomized trial of digoxin versus placebo. Lee, D.C., Johnson, R.A., Bingham, J.B., Leahy, M., Dinsmore, R.E., Goroll, A.H., Newell, J.B., Strauss, H.W., Haber, E. N. Engl. J. Med. (1982) [Pubmed]
  2. Granulocyte colony-stimulating factor in severe chemotherapy-induced afebrile neutropenia. Hartmann, L.C., Tschetter, L.K., Habermann, T.M., Ebbert, L.P., Johnson, P.S., Mailliard, J.A., Levitt, R., Suman, V.J., Witzig, T.E., Wieand, H.S., Miller, L.L., Moertel, C.G. N. Engl. J. Med. (1997) [Pubmed]
  3. The efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia. Hunninghake, D.B., Stein, E.A., Dujovne, C.A., Harris, W.S., Feldman, E.B., Miller, V.T., Tobert, J.A., Laskarzewski, P.M., Quiter, E., Held, J. N. Engl. J. Med. (1993) [Pubmed]
  4. Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease. Schreiber, S., Howaldt, S., Schnoor, M., Nikolaus, S., Bauditz, J., Gasché, C., Lochs, H., Raedler, A. N. Engl. J. Med. (1996) [Pubmed]
  5. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. Bensimon, G., Lacomblez, L., Meininger, V. N. Engl. J. Med. (1994) [Pubmed]
  6. A comparison of risperidone and haloperidol for the prevention of relapse in patients with schizophrenia. Csernansky, J.G., Mahmoud, R., Brenner, R. N. Engl. J. Med. (2002) [Pubmed]
  7. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. Le Bars, P.L., Katz, M.M., Berman, N., Itil, T.M., Freedman, A.M., Schatzberg, A.F. JAMA (1997) [Pubmed]
  8. Imipramine and chlordiazepoxide in depressive and anxiety disorders. I. Efficacy in depressed outpatients. Lipman, R.S., Covi, L., Rickels, K., McNair, D.M., Downing, R., Kahn, R.J., Lasseter, V.K., Faden, V. Arch. Gen. Psychiatry (1986) [Pubmed]
  9. Desipramine facilitation of initial cocaine abstinence. Gawin, F.H., Kleber, H.D., Byck, R., Rounsaville, B.J., Kosten, T.R., Jatlow, P.I., Morgan, C. Arch. Gen. Psychiatry (1989) [Pubmed]
  10. Double-blind parallel comparison of three dosages of sertraline and placebo in outpatients with obsessive-compulsive disorder. Greist, J., Chouinard, G., DuBoff, E., Halaris, A., Kim, S.W., Koran, L., Liebowitz, M., Lydiard, R.B., Rasmussen, S., White, K. Arch. Gen. Psychiatry (1995) [Pubmed]
  11. A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression. Keller, M.B., McCullough, J.P., Klein, D.N., Arnow, B., Dunner, D.L., Gelenberg, A.J., Markowitz, J.C., Nemeroff, C.B., Russell, J.M., Thase, M.E., Trivedi, M.H., Zajecka, J. N. Engl. J. Med. (2000) [Pubmed]
  12. Outpatient parenteral antimicrobial-drug therapy. Gilbert, D.N., Dworkin, R.J., Raber, S.R., Leggett, J.E. N. Engl. J. Med. (1997) [Pubmed]
  13. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. Finnish Study Group for Antimicrobial Resistance. Seppälä, H., Klaukka, T., Vuopio-Varkila, J., Muotiala, A., Helenius, H., Lager, K., Huovinen, P. N. Engl. J. Med. (1997) [Pubmed]
  14. A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis. Levine, M., Gent, M., Hirsh, J., Leclerc, J., Anderson, D., Weitz, J., Ginsberg, J., Turpie, A.G., Demers, C., Kovacs, M. N. Engl. J. Med. (1996) [Pubmed]
  15. Fluoxetine. Gram, L. N. Engl. J. Med. (1994) [Pubmed]
  16. Treatment of streptococcal endocarditis with a single daily dose of ceftriaxone sodium for 4 weeks. Efficacy and outpatient treatment feasibility. Francioli, P., Etienne, J., Hoigné, R., Thys, J.P., Gerber, A. JAMA (1992) [Pubmed]
  17. Response of thiazide-induced hypokalemia to amiloride. Maronde, R.F., Milgrom, M., Vlachakis, N.D., Chan, L. JAMA (1983) [Pubmed]
  18. Clindamycin and diarrhea. Friedman, G.D., Gerard, M.J., Ury, H.K. JAMA (1976) [Pubmed]
  19. Thromboprophylaxis with low-molecular-weight heparin in outpatients with plaster-cast immobilisation of the leg. Kock, H.J., Schmit-Neuerburg, K.P., Hanke, J., Rudofsky, G., Hirche, H. Lancet (1995) [Pubmed]
  20. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study. Petersen, P., Boysen, G., Godtfredsen, J., Andersen, E.D., Andersen, B. Lancet (1989) [Pubmed]
  21. Benzodiazepine withdrawal symptoms and propranolol. Tyrer, P., Rutherford, D., Huggett, T. Lancet (1981) [Pubmed]
  22. The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Weyand, C.M., Hicok, K.C., Conn, D.L., Goronzy, J.J. Ann. Intern. Med. (1992) [Pubmed]
  23. Reforming the core clerkship in internal medicine: the SGIM/CDIM Project. Society of General Internal Medicine/Clerkship Directors in Internal Medicine. Goroll, A.H., Morrison, G., Bass, E.B., Jablonover, R., Blackman, D., Platt, R., Whelan, A., Hekelman, F.P. Ann. Intern. Med. (2001) [Pubmed]
  24. Effect of timolol versus propranolol on hypertension and hemodynamics. Aronow, W.S., Ferlinz, J., Del Vicario, M., Moorthy, K., King, J., Cassidy, J. Circulation (1976) [Pubmed]
  25. Multiinstitutional phase II trial of paclitaxel, carboplatin, and concurrent radiation therapy for locally advanced non-small-cell lung cancer. Choy, H., Akerley, W., Safran, H., Graziano, S., Chung, C., Williams, T., Cole, B., Kennedy, T. J. Clin. Oncol. (1998) [Pubmed]
  26. Thyroid failure and protirelin (thyrotropin-releasing hormone) test abnormalities in depressed outpatients. Sternbach, H.A., Gold, M.S., Pottash, A.C., Extein, I. JAMA (1983) [Pubmed]
  27. Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: results from the Heart and Estrogen/Progestin Replacement Study (HERS) trial. Hlatky, M.A., Boothroyd, D., Vittinghoff, E., Sharp, P., Whooley, M.A. JAMA (2002) [Pubmed]
  28. Use of peripheral-blood progenitor cells abrogates the myelotoxicity of repetitive outpatient high-dose carboplatin and cyclophosphamide chemotherapy. Tepler, I., Cannistra, S.A., Frei, E., Gonin, R., Anderson, K.C., Demetri, G., Niloff, J., Goodman, H., Muntz, H., Muto, M. J. Clin. Oncol. (1993) [Pubmed]
  29. Paclitaxel plus carboplatin in advanced carcinoma of the urothelium: an active and tolerable outpatient regimen. Vaughn, D.J., Malkowicz, S.B., Zoltick, B., Mick, R., Ramchandani, P., Holroyde, C., Armstead, B., Fox, K., Wein, A. J. Clin. Oncol. (1998) [Pubmed]
  30. Conventional and molecular epidemiology of trimethoprim-sulfamethoxazole resistance among urinary Escherichia coli isolates. Burman, W.J., Breese, P.E., Murray, B.E., Singh, K.V., Batal, H.A., MacKenzie, T.D., Ogle, J.W., Wilson, M.L., Reves, R.R., Mehler, P.S. Am. J. Med. (2003) [Pubmed]
  31. A randomized study of outpatient treatment with ceftriaxone for selected febrile children with sickle cell disease. Wilimas, J.A., Flynn, P.M., Harris, S., Day, S.W., Smith, R., Chesney, P.J., Rodman, J.H., Eguiguren, J.M., Fairclough, D.L., Wang, W.C. N. Engl. J. Med. (1993) [Pubmed]
  32. Dexamethasone suppression test and response to antidepressants in depressed outpatients. Peselow, E.D., Fieve, R.R. N. Engl. J. Med. (1982) [Pubmed]
  33. A comparison of clozapine and haloperidol in hospitalized patients with refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Rosenheck, R., Cramer, J., Xu, W., Thomas, J., Henderson, W., Frisman, L., Fye, C., Charney, D. N. Engl. J. Med. (1997) [Pubmed]
  34. Abuse of cimetidine in outpatient practice. Brownlee, H.J., Delaney, R.A., Hancock, J.B. N. Engl. J. Med. (1983) [Pubmed]
  35. Monoclonal B lymphocytes with the characteristics of "indolent" chronic lymphocytic leukemia are present in 3.5% of adults with normal blood counts. Rawstron, A.C., Green, M.J., Kuzmicki, A., Kennedy, B., Fenton, J.A., Evans, P.A., O'Connor, S.J., Richards, S.J., Morgan, G.J., Jack, A.S., Hillmen, P. Blood (2002) [Pubmed]
  36. Concomitant administration of recombinant human interleukin-2 and recombinant interferon alfa-2A: an active outpatient regimen in metastatic renal cell carcinoma. Figlin, R.A., Belldegrun, A., Moldawer, N., Zeffren, J., deKernion, J. J. Clin. Oncol. (1992) [Pubmed]
  37. The genotypic distribution of shared-epitope DRB1 alleles suggests a recessive mode of inheritance of the rheumatoid arthritis disease-susceptibility gene. Evans, T.I., Han, J., Singh, R., Moxley, G. Arthritis Rheum. (1995) [Pubmed]
  38. Impaired insulin-induced glucose uptake by extrahepatic tissue is hallmark of NIDDM patients who have or will develop hypertension and microalbuminuria. Nosadini, R., Solini, A., Velussi, M., Muollo, B., Frigato, F., Sambataro, M., Cipollina, M.R., De Riva, F., Brocco, E., Crepaldi, G. Diabetes (1994) [Pubmed]
  39. Comprehensive analysis of the beta-myosin heavy chain gene in 389 unrelated patients with hypertrophic cardiomyopathy. Van Driest, S.L., Jaeger, M.A., Ommen, S.R., Will, M.L., Gersh, B.J., Tajik, A.J., Ackerman, M.J. J. Am. Coll. Cardiol. (2004) [Pubmed]
  40. Comparative effectiveness and costs of inpatient and outpatient detoxification of patients with mild-to-moderate alcohol withdrawal syndrome. Hayashida, M., Alterman, A.I., McLellan, A.T., O'Brien, C.P., Purtill, J.J., Volpicelli, J.R., Raphaelson, A.H., Hall, C.P. N. Engl. J. Med. (1989) [Pubmed]
  41. A multicenter trial of oral zidovudine in children with advanced human immunodeficiency virus disease. The Protocol 043 Study Group. McKinney, R.E., Maha, M.A., Connor, E.M., Feinberg, J., Scott, G.B., Wulfsohn, M., McIntosh, K., Borkowsky, W., Modlin, J.F., Weintrub, P. N. Engl. J. Med. (1991) [Pubmed]
  42. Cimetidine for anastomotic ulcers after partial gastrectomy. A randomized controlled trial. Gugler, R., Lindstaedt, H., Miederer, S., Möckel, W., Rohner, H.G., Schmitz, H., Székessy, T. N. Engl. J. Med. (1979) [Pubmed]
  43. Long-term diazepam therapy and clinical outcome. Rickels, K., Case, W.G., Downing, R.W., Winokur, A. JAMA (1983) [Pubmed]
  44. Clinical experience with penicillin skin testing in a large inner-city STD clinic. Gadde, J., Spence, M., Wheeler, B., Adkinson, N.F. JAMA (1993) [Pubmed]
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