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Disease relevance of Inpatients


Psychiatry related information on Inpatients


High impact information on Inpatients

  • Fluoxetine may be less effective than tricyclic antidepressant drugs for the treatment of inpatients with severe melancholic depression, and it should not be the first choice of a drug for them [11].
  • For all episodes of pain, the duration of inpatient analgesic therapy (intravenous and oral) was significantly shorter for the patients who received methylprednisolone than for those given placebo (mean, 41.3 vs 71.3 hours; P = 0.030) [12].
  • The inpatient program combined comprehensive psychiatric and medical evaluation, detoxification with oxazepam, and the initiation of rehabilitation treatment [13].
  • During that period, the mean length of hospitalization decreased (from 21.9 to 12.6 days; P less than 0.0001), inpatient physical therapy decreased (from 7.6 to 6.3 sessions; P less than 0.04), and the maximal distance walked before discharge fell (from 27 to 11 m [93 to 38 ft]; P less than 0.0001) [14].
  • DESIGN, SETTING, AND PARTICIPANTS: Representative samples of 390 patients from 2 methadone maintenance treatment programs (MMTPs) and 531 patients from 13 short-term residential substance abuse treatment (inpatient) programs, all in New York State, were surveyed in late 2000 and early 2001 [15].

Chemical compound and disease context of Inpatients


Biological context of Inpatients


Anatomical context of Inpatients

  • METHODS: We assayed cerebrospinal fluid for glutamate and obtained clinical symptom ratings in 19 medication-free (except p.r.n. chloral hydrate) schizophrenic or schizoaffective (typically with significant schizophrenic qualities) male inpatients [26].
  • In the present study, homovanillic acid in plasma (pHVA) and benzodiazepine receptors (3H-PK11195 binding) in neutrophil membranes were determined in blood obtained from cocaine-dependent (DSM-III-R) adult male inpatients at baseline-(within 72 hr of last cocaine use) and after 3 weeks of cocaine abstinence, and normal controls [27].
  • A 15-week double-blind, randomized, within-patient design was used to assess carbamazepine versus placebo as adjunctive treatment in chronic hospitalized psychiatric inpatients (predominantly schizophrenic) with EEG temporal lobe abnormalities but no clinical evidence of epilepsy [28].
  • The relative utility of steady-state (SS), plasma (Pl), and red blood cell (RBC) haloperidol levels for predicting clinical response was evaluated in a fixed-dose study in schizophrenic inpatients [29].
  • Cutaneous microcirculation was investigated in 30 major depressed inpatients receiving either 150 mg amitriptyline (n = 15) or 30 mg fluoxetine (n = 15) as monotherapy, and in 15 normal control subjects matched for age and sex [30].

Associations of Inpatients with chemical compounds

  • INTERVENTIONS--After baseline measures were obtained, subjects were randomly assigned to placebo or an 11-, 22-, or 44-mg/d dose of transdermal nicotine and admitted to a special hospital unit for intensive inpatient treatment of nicotine dependence [2].
  • Clonidine hydrochloride was administered to ten patients in an inpatient setting after abrupt discontinuation of chronic methadone hydrochloride administration [31].
  • Using Centers for Disease Control estimates of 18,720 patients diagnosed as having AIDS and alive during any part of 1985, we estimate that the total cost of inpatient care for patients with AIDS was $380 million for that year [32].
  • During the 6-day inpatient stay, daily nicotine and cotinine levels were determined from trough and peak blood samples [2].
  • METHODS: To evaluate the role of dopamine release by such cues, 20 cocaine-dependent inpatients were randomised in a single-dose, crossover, placebo-controlled design, to haloperidol (4 mg by mouth) and placebo [33].

Gene context of Inpatients


Analytical, diagnostic and therapeutic context of Inpatients


  1. Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group. Lowance, D., Neumayer, H.H., Legendre, C.M., Squifflet, J.P., Kovarik, J., Brennan, P.J., Norman, D., Mendez, R., Keating, M.R., Coggon, G.L., Crisp, A., Lee, I.C. N. Engl. J. Med. (1999) [Pubmed]
  2. High-dose nicotine patch therapy. Percentage of replacement and smoking cessation. Dale, L.C., Hurt, R.D., Offord, K.P., Lawson, G.M., Croghan, I.T., Schroeder, D.R. JAMA (1995) [Pubmed]
  3. Savings from outpatient antibiotic therapy for osteomyelitis. Economic analysis of a therapeutic strategy. Eisenberg, J.M., Kitz, D.S. JAMA (1986) [Pubmed]
  4. Double-blind, right/left comparison of calcipotriol and betamethasone valerate in treatment of psoriasis vulgaris. Kragballe, K., Gjertsen, B.T., De Hoop, D., Karlsmark, T., van de Kerkhof, P.C., Larkö, O., Nieboer, C., Roed-Petersen, J., Strand, A., Tikjøb, G. Lancet (1991) [Pubmed]
  5. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Frezza, M., Surrenti, C., Manzillo, G., Fiaccadori, F., Bortolini, M., Di Padova, C. Gastroenterology (1990) [Pubmed]
  6. Intravenous drug abuse and one academic health center. Dans, P.E., Matricciani, R.M., Otter, S.E., Reuland, D.S. JAMA (1990) [Pubmed]
  7. Psychiatric diagnoses of treatment-seeking cocaine abusers. Rounsaville, B.J., Anton, S.F., Carroll, K., Budde, D., Prusoff, B.A., Gawin, F. Arch. Gen. Psychiatry (1991) [Pubmed]
  8. The dexamethasone suppression test and response to methylphenidate in depression. Sternbach, H., Gwirtsman, H., Gerner, R.H. The American journal of psychiatry. (1981) [Pubmed]
  9. Double-blind comparison of addition of a second mood stabilizer versus an antidepressant to an initial mood stabilizer for treatment of patients with bipolar depression. Young, L.T., Joffe, R.T., Robb, J.C., MacQueen, G.M., Marriott, M., Patelis-Siotis, I. The American journal of psychiatry. (2000) [Pubmed]
  10. Relationship of serum haloperidol levels to clinical response in schizophrenic patients. Magliozzi, J.R., Hollister, L.E., Arnold, K.V., Earle, G.M. The American journal of psychiatry. (1981) [Pubmed]
  11. Fluoxetine. Gram, L. N. Engl. J. Med. (1994) [Pubmed]
  12. High-dose intravenous methylprednisolone therapy for pain in children and adolescents with sickle cell disease. Griffin, T.C., McIntire, D., Buchanan, G.R. N. Engl. J. Med. (1994) [Pubmed]
  13. Comparative effectiveness and costs of inpatient and outpatient detoxification of patients with mild-to-moderate alcohol withdrawal syndrome. Hayashida, M., Alterman, A.I., McLellan, A.T., O'Brien, C.P., Purtill, J.J., Volpicelli, J.R., Raphaelson, A.H., Hall, C.P. N. Engl. J. Med. (1989) [Pubmed]
  14. The care of elderly patients with hip fracture. Changes since implementation of the prospective payment system. Fitzgerald, J.F., Moore, P.S., Dittus, R.S. N. Engl. J. Med. (1988) [Pubmed]
  15. Prevalence and characteristics of chronic pain among chemically dependent patients in methadone maintenance and residential treatment facilities. Rosenblum, A., Joseph, H., Fong, C., Kipnis, S., Cleland, C., Portenoy, R.K. JAMA (2003) [Pubmed]
  16. Inpatient theophylline toxicity: preventable factors. Schiff, G.D., Hegde, H.K., LaCloche, L., Hryhorczuk, D.O. Ann. Intern. Med. (1991) [Pubmed]
  17. Alprazolam augmentation of the antipsychotic effects of fluphenazine in schizophrenic patients. Preliminary results. Wolkowitz, O.M., Breier, A., Doran, A., Kelsoe, J., Lucas, P., Paul, S.M., Pickar, D. Arch. Gen. Psychiatry (1988) [Pubmed]
  18. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Miller, J.S., Soignier, Y., Panoskaltsis-Mortari, A., McNearney, S.A., Yun, G.H., Fautsch, S.K., McKenna, D., Le, C., Defor, T.E., Burns, L.J., Orchard, P.J., Blazar, B.R., Wagner, J.E., Slungaard, A., Weisdorf, D.J., Okazaki, I.J., McGlave, P.B. Blood (2005) [Pubmed]
  19. Randomized phase II trial of infusional fluorouracil, epirubicin, and cyclophosphamide versus infusional fluorouracil, epirubicin, and cisplatin in patients with advanced breast cancer. Eisen, T., Smith, I.E., Johnston, S., Ellis, P.A., Prendiville, J., Seymour, M.T., Walsh, G., Ashley, S. J. Clin. Oncol. (1998) [Pubmed]
  20. Continuous versus inpatient prophylaxis of the first episode of spontaneous bacterial peritonitis with norfloxacin. Novella, M., Solà, R., Soriano, G., Andreu, M., Gana, J., Ortiz, J., Coll, S., Sàbat, M., Vila, M.C., Guarner, C., Vilardell, F. Hepatology (1997) [Pubmed]
  21. How well does the activated partial thromboplastin time predict postoperative hemorrhage? Suchman, A.L., Mushlin, A.I. JAMA (1986) [Pubmed]
  22. Causes of maternal mortality in Japan. Nagaya, K., Fetters, M.D., Ishikawa, M., Kubo, T., Koyanagi, T., Saito, Y., Sameshima, H., Sugimoto, M., Takagi, K., Chiba, Y., Honda, H., Mukubo, M., Kawamura, M., Satoh, S., Neki, R. JAMA (2000) [Pubmed]
  23. Abnormal resting regional cerebral blood flow patterns and their correlates in schizophrenia. Mathew, R.J., Wilson, W.H., Tant, S.R., Robinson, L., Prakash, R. Arch. Gen. Psychiatry (1988) [Pubmed]
  24. Magnetic resonance imaging in systemic lupus erythematosus patients without a history of neuropsychiatric lupus erythematosus. Jarek, M.J., West, S.G., Baker, M.R., Rak, K.M. Arthritis Rheum. (1994) [Pubmed]
  25. Vitamin A deficiency in Crohn's disease. Main, A.N., Mills, P.R., Russell, R.I., Bronte-Stewart, J., Nelson, L.M., McLelland, A., Shenkin, A. Gut (1983) [Pubmed]
  26. Cerebrospinal fluid glutamate inversely correlates with positive symptom severity in unmedicated male schizophrenic/schizoaffective patients. Faustman, W.O., Bardgett, M., Faull, K.F., Pfefferbaum, A., Csernansky, J.G. Biol. Psychiatry (1999) [Pubmed]
  27. Peripheral benzodiazepine receptors are decreased during cocaine withdrawal in humans. Javaid, J.I., Notorangelo, M.P., Pandey, S.C., Reddy, P.L., Pandey, G.N., Davis, J.M. Biol. Psychiatry (1994) [Pubmed]
  28. Carbamazepine as adjunctive treatment in nonepileptic chronic inpatients with EEG temporal lobe abnormalities. Neppe, V.M. The Journal of clinical psychiatry. (1983) [Pubmed]
  29. Comparative efficacy of red cell and plasma haloperidol as predictors of clinical response in schizophrenia. Smith, R.C., Baumgartner, R., Shvartsburd, A., Ravichandran, G.K., Vroulis, G., Mauldin, M. Psychopharmacology (Berl.) (1985) [Pubmed]
  30. Reflexes of the cutaneous microcirculation in amitriptyline and in fluoxetine treated patients. Mück-Weymann, M., Rechlin, T. Psychopharmacology (Berl.) (1996) [Pubmed]
  31. Opiate withdrawal using clonidine. A safe, effective, and rapid nonopiate treatment. Gold, M.S., Pottash, A.C., Sweeney, D.R., Kleber, H.D. JAMA (1980) [Pubmed]
  32. The provision and financing of medical care for AIDS patients in US public and private teaching hospitals. Andrulis, D.P., Beers, V.S., Bentley, J.D., Gage, L.S. JAMA (1987) [Pubmed]
  33. Haloperidol antagonism of cue-elicited cocaine craving. Berger, S.P., Hall, S., Mickalian, J.D., Reid, M.S., Crawford, C.A., Delucchi, K., Carr, K., Hall, S. Lancet (1996) [Pubmed]
  34. Outpatient biochemotherapy with interleukin-2 and interferon alfa-2b in patients with metastatic malignant melanoma: results of two phase II cytokine working group trials. Flaherty, L.E., Atkins, M., Sosman, J., Weiss, G., Clark, J.I., Margolin, K., Dutcher, J., Gordon, M.S., Lotze, M., Mier, J., Sorokin, P., Fisher, R.I., Appel, C., Du, W. J. Clin. Oncol. (2001) [Pubmed]
  35. Genetic predisposition to obesity in bulimia nervosa: a mutation screen of the melanocortin-4 receptor gene. Hebebrand, J., Fichter, M., Gerber, G., Görg, T., Hermann, H., Geller, F., Schäfer, H., Remschmidt, H., Hinney, A. Mol. Psychiatry (2002) [Pubmed]
  36. Decreased serum dipeptidyl peptidase IV activity in major depression. Maes, M., De Meester, I., Vanhoof, G., Scharpé, S., Bosmans, E., Vandervorst, C., Verkerk, R., Minner, B., Suy, E., Raus, J. Biol. Psychiatry (1991) [Pubmed]
  37. Prolonged elevation of interleukin-8 and interleukin-6 concentrations in plasma and of leukocyte interleukin-8 mRNA levels during septicemic and localized Pseudomonas pseudomallei infection. Friedland, J.S., Suputtamongkol, Y., Remick, D.G., Chaowagul, W., Strieter, R.M., Kunkel, S.L., White, N.J., Griffin, G.E. Infect. Immun. (1992) [Pubmed]
  38. Single nucleotide polymorphisms in genes for 2'-5'-oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection. Yakub, I., Lillibridge, K.M., Moran, A., Gonzalez, O.Y., Belmont, J., Gibbs, R.A., Tweardy, D.J. J. Infect. Dis. (2005) [Pubmed]
  39. Estrogen therapy for severe persistent depressions in women. Klaiber, E.L., Broverman, D.M., Vogel, W., Kobayashi, Y. Arch. Gen. Psychiatry (1979) [Pubmed]
  40. Dose-related ethanol-like effects of the NMDA antagonist, ketamine, in recently detoxified alcoholics. Krystal, J.H., Petrakis, I.L., Webb, E., Cooney, N.L., Karper, L.P., Namanworth, S., Stetson, P., Trevisan, L.A., Charney, D.S. Arch. Gen. Psychiatry (1998) [Pubmed]
  41. Effects of intrathecal thyrotropin-releasing hormone (protirelin) in refractory depressed patients. Marangell, L.B., George, M.S., Callahan, A.M., Ketter, T.A., Pazzaglia, P.J., L'Herrou, T.A., Leverich, G.S., Post, R.M. Arch. Gen. Psychiatry (1997) [Pubmed]
  42. Haloperidol. Plasma levels and prolactin response as predictors of clinical improvement in schizophrenia: chemical v radioreceptor plasma level assays. Smith, R.C., Baumgartner, R., Misra, C.H., Mauldin, M., Shvartsburd, A., Ho, B.T., DeJohn, C. Arch. Gen. Psychiatry (1984) [Pubmed]
  43. Rapid treatment of acute psychotic symptoms with high- and low-dose haloperidol. Behavioral considerations. Neborsky, R., Janowsky, D., Munson, E., Depry, D. Arch. Gen. Psychiatry (1981) [Pubmed]
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