- Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1. Tsukiyama-Kohara, K., Poulin, F., Kohara, M., DeMaria, C.T., Cheng, A., Wu, Z., Gingras, A.C., Katsume, A., Elchebly, M., Spiegelman, B.M., Harper, M.E., Tremblay, M.L., Sonenberg, N. Nat. Med. (2001)