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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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de Silva, R. et al.

de Silva, Hope, Pittman, Weale, Morris, Wood, Lees,

Strong association of the Saitohin gene Q7 variant with progressive supranuclear palsy.

Recent reports are inconclusive in showing that the Q7R polymorphism of the novel Saitohin gene, nested in intron 9 of the tau gene, is associated with AD. The authors show that this polymorphism is in complete linkage disequilibrium with the extended tau H1/H2 haplotype and that the Q variant and QQ genotype of Q7R are strongly associated with progressive supranuclear palsy, implicating it as a possibly important pathogenic candidate.[1]

References

Strong association of the Saitohin gene Q7 variant with progressive supranuclear palsy. de Silva, R., Hope, A., Pittman, A., Weale, M.E., Morris, H.R., Wood, N.W., Lees, A.J. Neurology (2003) [Pubmed]

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