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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Smibert, C.A. et al.

Identification and characterization of the virion- induced host shutoff product of herpes simplex virus gene UL41.

The virion- induced host shutoff product of the herpes simplex virus UL41 gene is required for shutoff of host translation and degradation of cellular mRNAs. We employed a rabbit antipeptide antiserum to identify a 58K UL41-related phosphoprotein in infected cells. We also provide evidence that this protein is a component of the virus particle, consistent with its role in virion-induced shutoff.[1]

References

Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41. Smibert, C.A., Johnson, D.C., Smiley, J.R. J. Gen. Virol. (1992) [Pubmed]

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