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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Niiro, H. et al.

Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1.

Adaptor proteins act as conduits to channel upstream signals into downstream effector branches. Two B cell-associated adaptors, Bam32 and Carma1, regulate the ERK, JNK, and NF-kappaB branches of the BCR signaling pathway. Recent studies of Bam32-/- and Carma1-/- mice suggest that each adaptor controls a distinct conduit regulating either only proliferation (Bam32) or both the proliferation and survival of B cells (Carma1).[1]

References

Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1. Niiro, H., Clark, E.A. Immunity (2003) [Pubmed]

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