- Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications. De Bonis, M.L., Cerase, A., Matarazzo, M.R., Ferraro, M., Strazzullo, M., Hansen, R.S., Chiurazzi, P., Neri, G., D'Esposito, M. Hum. Mol. Genet. (2006)