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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 

Iron metabolism meets signal transduction.

Mutations in hemojuvelin disrupt its ability to stimulate expression of the iron regulatory peptide hepcidin and result in the severe iron loading disorder juvenile hemochromatosis. A new study shows that hemojuvelin acts through the multifunctional bone morphogenetic protein pathway to modulate hepcidin levels, providing new insights into communication within a key physiological pathway.[1]

References

  1. Iron metabolism meets signal transduction. Anderson, G.J., Frazer, D.M. Nat. Genet. (2006)
 
 
 
 
 
 
 
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