- Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy. Hermann, M., Bogsrud, M.P., Molden, E., Asberg, A., Mohebi, B.U., Ose, L., Retterstøl, K. Clin. Pharmacol. Ther. (2006)