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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Behavioural changes in intravenous drug users in Geneva: rise and fall of HIV infection, 1980-1989.

In the early 1980s, more than 90% of intravenous drug users (IVDUs) shared needles and syringes in Geneva. The prevalence of antibodies to HIV in the sera of outpatient IVDUs increased from 6% in 1981 to 38% in 1983; it was, however, still only 37% in 1988. IVDUs starting methadone maintenance in 1987-1989 had a seroprevalence rate of 22%. In 1989 the percentage of IVDUs exchanging syringes and needles fell to only 5% of seropositive addicts. Only one seroconversion was observed in 1094 patient-months of observation in 1988-1989, which was probably due to sexual contact. The evidence suggests that, in the IDVUs studied, transmission of HIV has diminished since the early 1980s.[1]

References

  1. Behavioural changes in intravenous drug users in Geneva: rise and fall of HIV infection, 1980-1989. Robert, C.F., Déglon, J.J., Wintsch, J., Martin, J.L., Perrin, L., Bourquin, M., Gabriel, V., Hirschel, B. AIDS (1990) [Pubmed]
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