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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 

Sleep EEG and DST findings in anergic bipolar depression.

The authors report sleep EEG and dexamethasone suppression test (DST) findings for a homogeneous sample of anergic bipolar depressed outpatients (bipolar I, N = 7; bipolar II, N = 19) characterized by motor retardation, volitional inhibition, hypersomnia, or weight gain and sleep EEG findings for 26 age- and sex-matched normal control subjects. Sleep architecture was abnormal in bipolar depression, particularly with respect to little stage 1 sleep. The biological profile of an anergic episode of bipolar depression did not include a shorter than normal mean REM latency, poor sleep continuity, or abnormally low amounts of stages 3 and 4 sleep, and only three (13%) of 23 patients manifested cortisol nonsuppression.[1]

References

  1. Sleep EEG and DST findings in anergic bipolar depression. Thase, M.E., Himmelhoch, J.M., Mallinger, A.G., Jarrett, D.B., Kupfer, D.J. The American journal of psychiatry. (1989)
 
 
 
 
 
 
 
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