- Studies on the defect underlying the lysosomal storage of sialic acid in Salla disease. Lysosomal accumulation of sialic acid formed from N-acetyl-mannosamine or derived from low density lipoprotein in cultured mutant fibroblasts. Renlund, M., Kovanen, P.T., Raivio, K.O., Aula, P., Gahmberg, C.G., Ehnholm, C. J. Clin. Invest. (1986)