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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 136 documents. Results 1 - 10.

Drosophila melanogaster
Gene: ... Disease relevance of opa The results suggest the possibility that the opa- like domain... in humans. High impact information on opa opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster. Thus, opa does not act in a spatially... / Synonyms: Opa
Homo sapiens
Gene: ... in exon 14 of OPA1 causing an arginine- to- histidine change( R445H) in all affected members of the family...Disease relevance of OPA1 Nuclear gene OPA1, encoding a mitochondrial dynamin- related protein, is mutated in dominant optic atrophy. The heterozygous R445H mutation in OPA1 was found in five patients...
Homo sapiens
Gene: ... Disease relevance of OPA4 Two genes for dominantly inherited optic atrophy have been mapped( OPA1 and OPA4 ), of which the gene has been identified in one( OPA1). High impact information on OPA4 Three loci have been reported for ADOA: a major locus, harboring all identified mutations to date, maps to 3q...
Homo sapiens
Gene: ... High impact information on OPA5 Three loci have been reported for ADOA: a major locus, harboring all identified mutations to date, maps to 3q28( OPA1 ), a second locus is linked to 18q12. 2- q12. 3( OPA4) and a third locus on 22q12. 1- q13. 1( OPA5) has been reported recently....
Mus musculus
Gene: ... High impact information on Opa1 Gene structure and chromosomal localization of mouse Opa1: its exclusion from the Bst locus. Biological context of Opa1 Screening of the whole mRNA coding sequence and of the 31 exons of Opa1 did not reveal any mutation in Bst....
Homo sapiens
Gene: ... Disease relevance of OPA2 X- linked optic atrophy( OPA2) has been mapped but to date no gene has been identified. High impact information on OPA2 Twenty- four new localizations have been established, including five in previously reported conditions( FG, Carpenter, Arts, OPA2, and OFD1). A family with X...
Drosophila melanogaster
Gene: ... High impact information on msopa The Dromsopa opa repeat codes for the usual stretch of poly( glutamine) interrupted by histidine residues. The Dromsopa gene has no other identity with genes currently in the databases, once the opa repeat is excluded. The possibility that the Dromsopa gene is a male specific... / Synonyms: Male-specific opa-containing protein
Rattus norvegicus
Gene: ... High impact information on Opa1 However, aggregation of the mitochondrial network induced by the downregulation of Opa1 appears more frequent in RGCs than in control CGCs. Expression of the Opa1 mitochondrial... and neurites that colocalized with cytochrome c and Opa1. Analytical, diagnostic and therapeutic context of Opa...
Homo sapiens
Gene: ... Disease relevance of OPA3 Milder mutations in OPA3 should be sought in patients with optic atrophy... were normal, and because no patient had pathogenic sequence changes in the OPA1 or OPA3 genes. OPA3... patients with neurological abnormalities and 3- methylglutaconic aciduria( 3MGA) for mutations in the OPA3...
Drosophila melanogaster
Gene: Synonyms: OPA1; OPA1-like; Opa1-like

 

 
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