Robert S. Bitner
Neuroscience Research
Global Pharmaceutical Research and Development
Abbott Laboratories
100 Abbott Park Road
USA
Name/email consistency: high
- In-vivo histamine H(3) receptor antagonism activates cellular signaling suggestive of symptomatic and disease modifying efficacy in Alzheimer's disease. Bitner, R.S., Markosyan, S., Nikkel, A.L., Brioni, J.D. Neuropharmacology (2011)
- In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease. Bitner, R.S., Bunnelle, W.H., Decker, M.W., Drescher, K.U., Kohlhaas, K.L., Markosyan, S., Marsh, K.C., Nikkel, A.L., Browman, K., Radek, R., Anderson, D.J., Buccafusco, J., Gopalakrishnan, M. J. Pharmacol. Exp. Ther. (2010)
- Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo. Bitner, R.S., Nikkel, A.L., Markosyan, S., Otte, S., Puttfarcken, P., Gopalakrishnan, M. Brain Res. (2009)
- Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways. Bitner, R.S., Bunnelle, W.H., Anderson, D.J., Briggs, C.A., Buccafusco, J., Curzon, P., Decker, M.W., Frost, J.M., Gronlien, J.H., Gubbins, E., Li, J., Malysz, J., Markosyan, S., Marsh, K., Meyer, M.D., Nikkel, A.L., Radek, R.J., Robb, H.M., Timmermann, D., Sullivan, J.P., Gopalakrishnan, M. J. Neurosci. (2007)
- Dopamine D4 receptor signaling in the rat paraventricular hypothalamic nucleus: Evidence of natural coupling involving immediate early gene induction and mitogen activated protein kinase phosphorylation. Bitner, R.S., Nikkel, A.L., Otte, S., Martino, B., Barlow, E.H., Bhatia, P., Stewart, A.O., Brioni, J.D., Decker, M.W., Moreland, R.B. Neuropharmacology (2006)
- Alpha-7 nicotinic receptor expression by two distinct cell types in the dorsal raphe nucleus and locus coeruleus of rat. Bitner, R.S., Nikkel, A.L. Brain Res. (2002)
- Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat. Bitner, R.S., Nikkel, A.L., Curzon, P., Donnelly-Roberts, D.L., Puttfarcken, P.S., Namovic, M., Jacobs, I.C., Meyer, M.D., Decker, M.W. Brain Res. (2000)









