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Hari Shanker Sharma

Cerebrovascular Research Laboratory

Department of Surgical Sciences

Anesthesiology & Intensive Care Medicine

University Hospital

Sweden

[email]@surgsci.uu.se

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Cerebrovascular Research Laboratory, Department of Surgical Sciences, Anesthesiology & Intensive Care Medicine, University Hospital, Sweden. 2005 - 2012
  • Laboratory of Neurochemistry, Division of Neurotoxicology, National Center of Toxicological Research, Food and Drug Administration, USA. 2007 - 2008
  • Neurology Department, University of Cluj-Napoca, Romania. 2007

References

  1. Nanowired drug delivery to enhance neuroprotection in spinal cord injury. Tian, Z.R., Sharma, A., Nozari, A., Subramaniam, R., Lundstedt, T., Sharma, H.S. CNS. Neurol. Disord. Drug. Targets (2012) [Pubmed]
  2. Nanowired drug delivery of antioxidant compound h-290/51 enhances neuroprotection in hyperthermia-induced neurotoxicity. Muresanu, D.F., Sharma, A., Tian, Z.R., Smith, M.A., Sharma, H.S. CNS. Neurol. Disord. Drug. Targets (2012) [Pubmed]
  3. Cerebrolysin, a mixture of neurotrophic factors induces marked neuroprotection in spinal cord injury following intoxication of engineered nanoparticles from metals. Menon, P.K., Muresanu, D.F., Sharma, A., Mossler, H., Sharma, H.S. CNS. Neurol. Disord. Drug. Targets (2012) [Pubmed]
  4. Diabetes exacerbates nanoparticles induced brain pathology. Lafuente, J.V., Sharma, A., Patnaik, R., Muresanu, D.F., Sharma, H.S. CNS. Neurol. Disord. Drug. Targets (2012) [Pubmed]
  5. Neurotoxicity of engineered nanoparticles from metals. Sharma, H.S., Sharma, A. CNS. Neurol. Disord. Drug. Targets (2012) [Pubmed]
  6. Nanowired drug delivery for neuroprotection in central nervous system injuries: modulation by environmental temperature, intoxication of nanoparticles, and comorbidity factors. Sharma, H.S., Sharma, A. Wiley Interdisciplinary Reviews. Nanomedicine Nanobiotechnology (2011) [Pubmed]
  7. Cardiac arrest-induced regional blood-brain barrier breakdown, edema formation and brain pathology: a light and electron microscopic study on a new model for neurodegeneration and neuroprotection in porcine brain. Sharma, H.S., Miclescu, A., Wiklund, L. J. Neural. Transm (2011) [Pubmed]
  8. New perspectives on molecular and cellular mechanisms of neuroprotection and neuroregeneration: part I. Sharma, H.S., Sharma, A. Expert. Rev. Neurother (2010) [Pubmed]
  9. A combination of tumor necrosis factor-alpha and neuronal nitric oxide synthase antibodies applied topically over the traumatized spinal cord enhances neuroprotection and functional recovery in the rat. Sharma, H.S. Ann. N. Y. Acad. Sci. (2010) [Pubmed]
  10. Cerebrolysin treatment attenuates heat shock protein overexpression in the brain following heat stress: an experimental study using immunohistochemistry at light and electron microscopy in the rat. Sharma, H.S., Muresanu, D., Sharma, A., Zimmermann-Meinzingen, S. Ann. N. Y. Acad. Sci. (2010) [Pubmed]
  11. Cerebrolysin reduces blood-cerebrospinal fluid barrier permeability change, brain pathology, and functional deficits following traumatic brain injury in the rat. Sharma, H.S., Zimmermann-Meinzingen, S., Johanson, C.E. Ann. N. Y. Acad. Sci. (2010) [Pubmed]
  12. Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats. Sharma, H.S., Hussain, S., Schlager, J., Ali, S.F., Sharma, A. Acta Neurochir. Suppl. (2010) [Pubmed]
  13. A new antioxidant compound H-290/51 attenuates nanoparticle induced neurotoxicity and enhances neurorepair in hyperthermia. Sharma, H.S., Sharma, A., Hussain, S., Schlager, J., Sjöquist, P.O., Muresanu, D. Acta Neurochir. Suppl. (2010) [Pubmed]
  14. Nanowired-drug delivery enhances neuroprotective efficacy of compounds and reduces spinal cord edema formation and improves functional outcome following spinal cord injury in the rat. Sharma, H.S., Ali, S.F., Tian, Z.R., Patnaik, R., Patnaik, S., Sharma, A., Boman, A., Lek, P., Seifert, E., Lundstedt, T. Acta Neurochir. Suppl. (2010) [Pubmed]
  15. Cerebrolysin attenuates blood-brain barrier and brain pathology following whole body hyperthermia in the rat. Sharma, H.S., Zimmermann-Meinzingen, S., Sharma, A., Johanson, C.E. Acta Neurochir. Suppl. (2010) [Pubmed]
  16. Antibodies to dynorphin a (1-17) attenuate closed head injury induced blood-brain barrier disruption, brain edema formation and brain pathology in the rat. Sharma, H.S., Patnaik, R., Patnaik, S., Sharma, A., Mohanty, S., Vannemreddy, P. Acta Neurochir. Suppl. (2010) [Pubmed]
  17. Alterations in blood-brain barrier function and brain pathology by morphine in the rat. Neuroprotective effects of antioxidant H-290/51. Sharma, H.S., Sjöquist, P.O., Ali, S.F. Acta Neurochir. Suppl. (2010) [Pubmed]
  18. New perspectives on molecular and cellular mechanisms of neuroprotection and neuroregeneration: part II. Sharma, H.S., Sharma, A. Expert. Rev. Neurother (2010) [Pubmed]
  19. Selected combination of neurotrophins potentiate neuroprotection and functional recovery following spinal cord injury in the rat. Sharma, H.S. Acta Neurochir. Suppl. (2010) [Pubmed]
  20. Rapid morphological brain abnormalities during acute methamphetamine intoxication in the rat: an experimental study using light and electron microscopy. Sharma, H.S., Kiyatkin, E.A. J. Chem. Neuroanat. (2009) [Pubmed]
  21. Conference Scene: New perspectives on nanoneuroscience, nanoneuropharmacology and nanoneurotoxicology. Sharma, H.S., Sharma, A. Nanomedicine. (Lond) (2009) [Pubmed]
  22. 6th Global College of Neuroprotection and Neuroregeneration, annual meeting. Sharma, H.S., Sharma, A. Expert. Rev. Neurother (2009) [Pubmed]
  23. Chapter 9 - Nanoparticles influence pathophysiology of spinal cord injury and repair. Sharma, H.S., Muresanu, D.F., Sharma, A., Patnaik, R., Lafuente, J.V. Prog. Brain Res. (2009) [Pubmed]
  24. Acute administration of 3,4-methylenedioxymethamphetamine induces profound hyperthermia, blood-brain barrier disruption, brain edema formation, and cell injury. Sharma, H.S., Ali, S.F. Ann. N. Y. Acad. Sci. (2008) [Pubmed]
  25. 5th Annual Global College of Neuroprotection and Neuroregeneration. Sharma, H.S. Expert. Rev. Neurother (2008) [Pubmed]
  26. New perspectives for the treatment options in spinal cord injury. Sharma, H.S. Expert. Opin. Pharmacother (2008) [Pubmed]
  27. Antibodies to serotonin attenuate closed head injury induced blood brain barrier disruption and brain pathology. Sharma, H.S., Patnaik, R., Patnaik, S., Mohanty, S., Sharma, A., Vannemreddy, P. Ann. N. Y. Acad. Sci. (2007) [Pubmed]
  28. Drug delivery to the spinal cord tagged with nanowire enhances neuroprotective efficacy and functional recovery following trauma to the rat spinal cord. Sharma, H.S., Ali, S.F., Dong, W., Tian, Z.R., Patnaik, R., Patnaik, S., Sharma, A., Boman, A., Lek, P., Seifert, E., Lundstedt, T. Ann. N. Y. Acad. Sci. (2007) [Pubmed]
  29. Intracerebroventricularly administered neurotrophins attenuate blood cerebrospinal fluid barrier breakdown and brain pathology following whole-body hyperthermia: an experimental study in the rat using biochemical and morphological approaches. Sharma, H.S., Johanson, C.E. Ann. N. Y. Acad. Sci. (2007) [Pubmed]
  30. A select combination of neurotrophins enhances neuroprotection and functional recovery following spinal cord injury. Sharma, H.S. Ann. N. Y. Acad. Sci. (2007) [Pubmed]
  31. Chronic hypertension aggravates heat stress induced cognitive dysfunction and brain pathology: an experimental study in the rat, using growth hormone therapy for possible neuroprotection. Muresanu, D.F., Sharma, H.S. Ann. N. Y. Acad. Sci. (2007) [Pubmed]
  32. Neuroprotective effects of melanocortins in CNS injury. Sharma, H.S., Lundstedt, T., Flärdh, M., Skottner, A., Wiklund, L. Curr. Pharm. Des. (2007) [Pubmed]
  33. Interaction between amino acid neurotransmitters and opioid receptors in hyperthermia-induced brain pathology. Sharma, H.S. Prog. Brain Res. (2007) [Pubmed]
  34. Nanoparticles aggravate heat stress induced cognitive deficits, blood-brain barrier disruption, edema formation and brain pathology. Sharma, H.S., Sharma, A. Prog. Brain Res. (2007) [Pubmed]
  35. Methods to produce hyperthermia-induced brain dysfunction. Sharma, H.S. Prog. Brain Res. (2007) [Pubmed]
  36. Drugs of abuse-induced hyperthermia, blood-brain barrier dysfunction and neurotoxicity: neuroprotective effects of a new antioxidant compound H-290/51. Sharma, H.S., Sjöquist, P.O., Ali, S.F. Curr. Pharm. Des. (2007) [Pubmed]
  37. Neurotrophic factors in combination: a possible new therapeutic strategy to influence pathophysiology of spinal cord injury and repair mechanisms. Sharma, H.S. Curr. Pharm. Des. (2007) [Pubmed]
  38. 10th International Conference on Amino Acids and Protein. Sharma, H.S. Expert. Rev. Neurother (2007) [Pubmed]
  39. 4th Global College of Neuroprotection and Neuroregeneration meeting. Sharma, H.S. Expert. Rev. Neurother (2007) [Pubmed]
  40. Spinal cord injury induced heat shock protein expression is reduced by an antioxidant compound H-290/51. An experimental study using light and electron microscopy in the rat. Sharma, H.S., Gordh, T., Wiklund, L., Mohanty, S., Sjöquist, P.O. J. Neural. Transm (2006) [Pubmed]
  41. Intracerebral administration of neuronal nitric oxide synthase antiserum attenuates traumatic brain injury-induced blood-brain barrier permeability, brain edema formation, and sensory motor disturbances in the rat. Sharma, H.S., Wiklund, L., Badgaiyan, R.D., Mohanty, S., Alm, P. Acta Neurochir. Suppl. (2006) [Pubmed]
  42. Topical application of dynorphin A (1-17) antibodies attenuates neuronal nitric oxide synthase up-regulation, edema formation, and cell injury following focal trauma to the rat spinal cord. Sharma, H.S., Nyberg, F., Gordh, T., Alm, P. Acta Neurochir. Suppl. (2006) [Pubmed]
  43. Histamine receptors influence blood-spinal cord barrier permeability, edema formation, and spinal cord blood flow following trauma to the rat spinal cord. Sharma, H.S., Vannemreddy, P., Patnaik, R., Patnaik, S., Mohanty, S. Acta Neurochir. Suppl. (2006) [Pubmed]
  44. Post-injury treatment with a new antioxidant compound H-290/51 attenuates spinal cord trauma-induced c-fos expression, motor dysfunction, edema formation, and cell injury in the rat. Sharma, H.S., Sjöquist, P.O., Mohanty, S., Wiklund, L. Acta Neurochir. Suppl. (2006) [Pubmed]
  45. Post-traumatic application of brain-derived neurotrophic factor and glia-derived neurotrophic factor on the rat spinal cord enhances neuroprotection and improves motor function. Sharma, H.S. Acta Neurochir. Suppl. (2006) [Pubmed]
  46. Whole-body hyperthermia in the rat disrupts the blood-cerebrospinal fluid barrier and induces brain edema. Sharma, H.S., Duncan, J.A., Johanson, C.E. Acta Neurochir. Suppl. (2006) [Pubmed]
  47. Hyperthermia induced brain oedema: current status and future perspectives. Sharma, H.S. Indian J. Med. Res. (2006) [Pubmed]
  48. Alterations in blood-brain barrier function by morphine and methamphetamine. Sharma, H.S., Ali, S.F. Ann. N. Y. Acad. Sci. (2006) [Pubmed]
  49. A potent serotonin-modulating compound AP-267 attenuates morphine withdrawal-induced blood-brain barrier dysfunction in rats. Sharma, H.S., Lundstedt, T., Boman, A., Lek, P., Seifert, E., Wiklund, L., Ali, S.F. Ann. N. Y. Acad. Sci. (2006) [Pubmed]
  50. Pathophysiology of blood-spinal cord barrier in traumatic injury and repair. Sharma, H.S. Curr. Pharm. Des. (2005) [Pubmed]
  51. Neuroprotective effects of neurotrophins and melanocortins in spinal cord injury: an experimental study in the rat using pharmacological and morphological approaches. Sharma, H.S. Ann. N. Y. Acad. Sci. (2005) [Pubmed]
  52. Neuroprotective effects of nitric oxide synthase inhibitors in spinal cord injury-induced pathophysiology and motor functions: an experimental study in the rat. Sharma, H.S., Badgaiyan, R.D., Alm, P., Mohanty, S., Wiklund, L. Ann. N. Y. Acad. Sci. (2005) [Pubmed]
 
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