John Silke
Walter and Eliza Hall Institute of Medical Research
Post Office Royal Melbourne Hospital
Victoria
Australia
Name/email consistency: high
- Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance. Silke, J., Kratina, T., Chu, D., Ekert, P.G., Day, C.L., Pakusch, M., Huang, D.C., Vaux, D.L. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis. Silke, J., Kratina, T., Ekert, P.G., Pakusch, M., Vaux, D.L. J. Biol. Chem. (2004)
- The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites. Silke, J., Hawkins, C.J., Ekert, P.G., Chew, J., Day, C.L., Pakusch, M., Verhagen, A.M., Vaux, D.L. J. Cell Biol. (2002)
- Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP. Silke, J., Ekert, P.G., Day, C.L., Hawkins, C.J., Baca, M., Chew, J., Pakusch, M., Verhagen, A.M., Vaux, D.L. EMBO J. (2001)
- Cell death: shadow baxing. Silke, J., Vaux, D.L. Curr. Biol. (1998)
