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Wataru Shimizu

Division of Arrhythmia and Electrophysiology

Department of Cardiovascular Medicine

National Cerebral and Cardiovascular Center




Name/email consistency: high



  • Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan. 2000 - 2010
  • National Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, 5-7-1 Fujishiro-dai, Japan. 2005 - 2008


  1. How the knowledge of genetic "makeup" and cellular data can affect the analysis of repolarization in surface electrocardiogram. Shimizu, W. J. Electrocardiol (2010) [Pubmed]
  2. Genotype-phenotype aspects of type 2 long QT syndrome. Shimizu, W., Moss, A.J., Wilde, A.A., Towbin, J.A., Ackerman, M.J., January, C.T., Tester, D.J., Zareba, W., Robinson, J.L., Qi, M., Vincent, G.M., Kaufman, E.S., Hofman, N., Noda, T., Kamakura, S., Miyamoto, Y., Shah, S., Amin, V., Goldenberg, I., Andrews, M.L., McNitt, S. J. Am. Coll. Cardiol. (2009) [Pubmed]
  3. Arrhythmias originating from the right ventricular outflow tract: how to distinguish "malignant" from "benign"? Shimizu, W. Heart. Rhythm (2009) [Pubmed]
  4. Clinical impact of genetic studies in lethal inherited cardiac arrhythmias. Shimizu, W. Circ. J. (2008) [Pubmed]
  5. Genetics of congenital long QT syndrome and Brugada syndrome. Shimizu, W. Future. Cardiol (2008) [Pubmed]
  6. Sex hormone and gender difference--role of testosterone on male predominance in Brugada syndrome. Shimizu, W., Matsuo, K., Kokubo, Y., Satomi, K., Kurita, T., Noda, T., Nagaya, N., Suyama, K., Aihara, N., Kamakura, S., Inamoto, N., Akahoshi, M., Tomoike, H. J. Cardiovasc. Electrophysiol. (2007) [Pubmed]
  7. Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome. Shimizu, W., Aiba, T., Antzelevitch, C. Curr. Pharm. Des. (2005) [Pubmed]
  8. The long QT syndrome: therapeutic implications of a genetic diagnosis. Shimizu, W. Cardiovasc. Res. (2005) [Pubmed]
  9. Mechanisms of disease: current understanding and future challenges in Brugada syndrome. Shimizu, W., Aiba, T., Kamakura, S. Nature Clinical Practice. Cardiovascular Medicine (2005) [Pubmed]
  10. Acquired forms of the Brugada syndrome. Shimizu, W. J. Electrocardiol (2005) [Pubmed]
  11. Implications and problems of the Sudden Cardiac Death in Heart Failure Trial. Shimizu, W., Satomi, K. Future. Cardiol (2005) [Pubmed]
  12. Mutation site-specific differences in arrhythmic risk and sensitivity to sympathetic stimulation in the LQT1 form of congenital long QT syndrome: multicenter study in Japan. Shimizu, W., Horie, M., Ohno, S., Takenaka, K., Yamaguchi, M., Shimizu, M., Washizuka, T., Aizawa, Y., Nakamura, K., Ohe, T., Aiba, T., Miyamoto, Y., Yoshimasa, Y., Towbin, J.A., Priori, S.G., Kamakura, S. J. Am. Coll. Cardiol. (2004) [Pubmed]
  13. Diagnostic value of epinephrine test for genotyping LQT1, LQT2, and LQT3 forms of congenital long QT syndrome. Shimizu, W., Noda, T., Takaki, H., Nagaya, N., Satomi, K., Kurita, T., Suyama, K., Aihara, N., Sunagawa, K., Echigo, S., Miyamoto, Y., Yoshimasa, Y., Nakamura, K., Ohe, T., Towbin, J.A., Priori, S.G., Kamakura, S. Heart. Rhythm (2004) [Pubmed]
  14. Epinephrine unmasks latent mutation carriers with LQT1 form of congenital long-QT syndrome. Shimizu, W., Noda, T., Takaki, H., Kurita, T., Nagaya, N., Satomi, K., Suyama, K., Aihara, N., Kamakura, S., Sunagawa, K., Echigo, S., Nakamura, K., Ohe, T., Towbin, J.A., Napolitano, C., Priori, S.G. J. Am. Coll. Cardiol. (2003) [Pubmed]
  15. Genotype-specific clinical manifestation in long QT syndrome. Shimizu, W. Expert. Rev. Cardiovasc. Ther (2003) [Pubmed]
  16. Differential effects of beta-blockade on dispersion of repolarization in the absence and presence of sympathetic stimulation between the LQT1 and LQT2 forms of congenital long QT syndrome. Shimizu, W., Tanabe, Y., Aiba, T., Inagaki, M., Kurita, T., Suyama, K., Nagaya, N., Taguchi, A., Aihara, N., Sunagawa, K., Nakamura, K., Ohe, T., Towbin, J.A., Priori, S.G., Kamakura, S. J. Am. Coll. Cardiol. (2002) [Pubmed]
  17. Images in cardiology: Visualisation of activation and repolarisation in congenital long QT syndrome. Shimizu, W., Satomi, K., Kamakura, S. Heart (2002) [Pubmed]
  18. Effects of sympathetic stimulation on various repolarization indices in the congenital long QT syndrome. Shimizu, W. Ann. Noninvasive. Electrocardiol (2002) [Pubmed]
  19. Catecholamines in children with congenital long QT syndrome and Brugada syndrome. Shimizu, W., Kamakura, S. J. Electrocardiol (2001) [Pubmed]
  20. Paradoxic abbreviation of repolarization in epicardium of the right ventricular outflow tract during augmentation of Brugada-type ST segment elevation. Shimizu, W., Aiba, T., Kurita, T., Kamakura, S. J. Cardiovasc. Electrophysiol. (2001) [Pubmed]
  21. Body surface distribution and response to drugs of ST segment elevation in Brugada syndrome: clinical implication of eighty-seven-lead body surface potential mapping and its application to twelve-lead electrocardiograms. Shimizu, W., Matsuo, K., Takagi, M., Tanabe, Y., Aiba, T., Taguchi, A., Suyama, K., Kurita, T., Aihara, N., Kamakura, S. J. Cardiovasc. Electrophysiol. (2000) [Pubmed]
  22. Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. Shimizu, W., Antzelevitch, C., Suyama, K., Kurita, T., Taguchi, A., Aihara, N., Takaki, H., Sunagawa, K., Kamakura, S. J. Cardiovasc. Electrophysiol. (2000) [Pubmed]
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