Chuang Lu
Drug Metabolism and Pharmacokinetics
Millennium Pharmaceuticals
Inc., Cambridge
MA 02139
USA
Name/email consistency: high
- Quantitative prediction and clinical observation of a CYP3A inhibitor-based drug-drug interactions with MLN3897, a potent C-C chemokine receptor-1 antagonist. Lu, C., Balani, S.K., Qian, M.G., Prakash, S.R., Ducray, P.S., von Moltke, L.L. J. Pharmacol. Exp. Ther. (2010)
- Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. II. In vitro-in vivo correlation with ketoconazole. Lu, C., Hatsis, P., Berg, C., Lee, F.W., Balani, S.K. Drug Metab. Dispos. (2008)
- Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. III. In vitro-in vivo correlation with fluconazole. Lu, C., Berg, C., Prakash, S.R., Lee, F.W., Balani, S.K. Drug Metab. Dispos. (2008)
- A novel model for the prediction of drug-drug interactions in humans based on in vitro cytochrome p450 phenotypic data. Lu, C., Miwa, G.T., Prakash, S.R., Gan, L.S., Balani, S.K. Drug Metab. Dispos. (2007)
- Investigation of drug-drug interaction potential of bortezomib in vivo in female Sprague-Dawley rats and in vitro in human liver microsomes. Lu, C., Gallegos, R., Li, P., Xia, C.Q., Pusalkar, S., Uttamsingh, V., Nix, D., Miwa, G.T., Gan, L.S. Drug Metab. Dispos. (2006)
- Comparison of intrinsic clearance in liver microsomes and hepatocytes from rats and humans: evaluation of free fraction and uptake in hepatocytes. Lu, C., Li, P., Gallegos, R., Uttamsingh, V., Xia, C.Q., Miwa, G.T., Balani, S.K., Gan, L.S. Drug Metab. Dispos. (2006)