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Charles N. Serhan

1 Harvard Institutes of Medicine

77 Ave. Louis Pasteur

HIM 829

Boston

[email]@*.bwh.harvard.edu

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • 1 Harvard Institutes of Medicine, 77 Ave. Louis Pasteur, HIM 829, Boston. 2012
  • Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesia, Perioperative and Pain Medicine, Harvard Institute of Medicine, USA. 1999 - 2011

References

  1. Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. Serhan, C.N., Dalli, J., Karamnov, S., Choi, A., Park, C.K., Xu, Z.Z., Ji, R.R., Zhu, M., Petasis, N.A. FASEB J. (2012) [Pubmed]
  2. Novel anti-inflammatory--pro-resolving mediators and their receptors. Serhan, C.N., Krishnamoorthy, S., Recchiuti, A., Chiang, N. Curr. Top. Med. Chem (2011) [Pubmed]
  3. Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not? Serhan, C.N. Am. J. Pathol. (2010) [Pubmed]
  4. Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions. Serhan, C.N., Yang, R., Martinod, K., Kasuga, K., Pillai, P.S., Porter, T.F., Oh, S.F., Spite, M. J. Exp. Med. (2009) [Pubmed]
  5. Systems approach to inflammation resolution: identification of novel anti-inflammatory and pro-resolving mediators. Serhan, C.N. J. Thromb. Haemost. (2009) [Pubmed]
  6. Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus. Serhan, C.N., Chiang, N. Br. J. Pharmacol. (2008) [Pubmed]
  7. Anti-inflammatory and proresolving lipid mediators. Serhan, C.N., Yacoubian, S., Yang, R. Annu. Rev. Pathol (2008) [Pubmed]
  8. Controlling the resolution of acute inflammation: a new genus of dual anti-inflammatory and proresolving mediators. Serhan, C.N. J. Periodontol. (2008) [Pubmed]
  9. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Serhan, C.N., Chiang, N., Van Dyke, T.E. Nat. Rev. Immunol. (2008) [Pubmed]
  10. Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators. Serhan, C.N. Prostaglandins Leukot. Essent. Fatty Acids (2008) [Pubmed]
  11. Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Serhan, C.N. Annu. Rev. Immunol. (2007) [Pubmed]
  12. Resolution of inflammation: state of the art, definitions and terms. Serhan, C.N., Brain, S.D., Buckley, C.D., Gilroy, D.W., Haslett, C., O'Neill, L.A., Perretti, M., Rossi, A.G., Wallace, J.L. FASEB J. (2007) [Pubmed]
  13. Novel chemical mediators in the resolution of inflammation: resolvins and protectins. Serhan, C.N. Anesthesiol. Clin (2006) [Pubmed]
  14. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. Serhan, C.N., Gotlinger, K., Hong, S., Lu, Y., Siegelman, J., Baer, T., Yang, R., Colgan, S.P., Petasis, N.A. J. Immunol. (2006) [Pubmed]
  15. Lipid mediator informatics-lipidomics: novel pathways in mapping resolution. Serhan, C.N., Hong, S., Lu, Y. AAPS. J (2006) [Pubmed]
  16. The allergy archives: pioneer and milestones. The discovery and characterization of the leukotrienes. Serhan, C.N., Wasserman, S.I. J. Allergy Clin. Immunol. (2006) [Pubmed]
  17. Novel omega -- 3-derived local mediators in anti-inflammation and resolution. Serhan, C.N. Pharmacol. Ther. (2005) [Pubmed]
  18. Novel eicosanoid and docosanoid mediators: resolvins, docosatrienes, and neuroprotectins. Serhan, C.N. Curr. Opin. Clin. Nutr. Metab. Care (2005) [Pubmed]
  19. Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. Serhan, C.N. Prostaglandins Leukot. Essent. Fatty Acids (2005) [Pubmed]
  20. Mediator lipidomics. Serhan, C.N. Prostaglandins Other Lipid Mediat. (2005) [Pubmed]
  21. Resolution of inflammation: the beginning programs the end. Serhan, C.N., Savill, J. Nat. Immunol. (2005) [Pubmed]
  22. Novel endogenous small molecules as the checkpoint controllers in inflammation and resolution: entrée for resoleomics. Serhan, C.N., Chiang, N. Rheum. Dis. Clin. North Am. (2004) [Pubmed]
  23. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis. Serhan, C.N., Gotlinger, K., Hong, S., Arita, M. Prostaglandins Other Lipid Mediat. (2004) [Pubmed]
  24. A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution. Serhan, C.N. Histochem. Cell Biol. (2004) [Pubmed]
  25. Clues for new therapeutics in osteoporosis and periodontal disease: new roles for lipoxygenases?. Serhan, C.N. Expert Opin. Ther. Targets (2004) [Pubmed]
  26. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers. Serhan, C.N., Arita, M., Hong, S., Gotlinger, K. Lipids (2004) [Pubmed]
  27. Success of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics. Serhan, C.N., Levy, B. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  28. Novel pathways and endogenous mediators in anti-inflammation and resolution. Serhan, C.N., Levy, B. Chem. Immunol. Allergy (2003) [Pubmed]
  29. Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. Serhan, C.N., Jain, A., Marleau, S., Clish, C., Kantarci, A., Behbehani, B., Colgan, S.P., Stahl, G.L., Merched, A., Petasis, N.A., Chan, L., Van Dyke, T.E. J. Immunol. (2003) [Pubmed]
  30. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. Serhan, C.N., Hong, S., Gronert, K., Colgan, S.P., Devchand, P.R., Mirick, G., Moussignac, R.L. J. Exp. Med. (2002) [Pubmed]
  31. Lipid-derived mediators in endogenous anti-inflammation and resolution: lipoxins and aspirin-triggered 15-epi-lipoxins. Serhan, C.N., Chiang, N. ScientificWorldJournal (2002) [Pubmed]
  32. Cutting edge: nociceptin stimulates neutrophil chemotaxis and recruitment: inhibition by aspirin-triggered-15-epi-lipoxin A4. Serhan, C.N., Fierro, I.M., Chiang, N., Pouliot, M. J. Immunol. (2001) [Pubmed]
  33. Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways. Serhan, C.N., Oliw, E. J. Clin. Invest. (2001) [Pubmed]
  34. Novel antiinflammatory targets for asthma. A role for PPARgamma?. Serhan, C.N., Devchand, P.R. Am. J. Respir. Cell Mol. Biol. (2001) [Pubmed]
  35. Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side. Serhan, C.N. Arch. Immunol. Ther. Exp. (Warsz.) (2001) [Pubmed]
  36. The scent of a phagocyte: Advances on leukotriene b(4) receptors. Serhan, C.N., Prescott, S.M. J. Exp. Med. (2000) [Pubmed]
  37. Aspirin triggered lipid mediators: novel inhibitors of leucocyte trafficking. Serhan, C.N., Clish, C.B. Thorax (2000) [Pubmed]
  38. Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions. Serhan, C.N., Clish, C.B., Brannon, J., Colgan, S.P., Gronert, K., Chiang, N. J. Physiol. Pharmacol. (2000) [Pubmed]
  39. Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators. Serhan, C.N., Takano, T., Gronert, K., Chiang, N., Clish, C.B. Clin. Chem. Lab. Med. (1999) [Pubmed]
 
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