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Daniel Kirchhofer

Department of Early Discovery Biochemistry

Genentech

Inc., 1 DNA Way

MS #27

[email]@gene.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Early Discovery Biochemistry, Genentech, Inc., 1 DNA Way, MS #27. 2011
  • Departments of Cardiovascular Research and Protein Engineering, Genentech, Inc., South San Francisco, California 94080, USA. 2000 - 2007

References

  1. Proteolytic activation of pro-macrophage-stimulating protein by hepsin. Ganesan, R., Kolumam, G.A., Lin, S.J., Xie, M.H., Santell, L., Wu, T.D., Lazarus, R.A., Chaudhuri, A., Kirchhofer, D. Mol. Cancer Res. (2011) [Pubmed]
  2. Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist. Kirchhofer, D., Lipari, M.T., Santell, L., Billeci, K.L., Maun, H.R., Sandoval, W.N., Moran, P., Ridgway, J., Eigenbrot, C., Lazarus, R.A. Proc. Natl. Acad. Sci. U.S.A. (2007) [Pubmed]
  3. Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling. Kirchhofer, D., Yao, X., Peek, M., Eigenbrot, C., Lipari, M.T., Billeci, K.L., Maun, H.R., Moran, P., Santell, L., Wiesmann, C., Lazarus, R.A. J. Biol. Chem. (2004) [Pubmed]
  4. Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1. Kirchhofer, D., Peek, M., Li, W., Stamos, J., Eigenbrot, C., Kadkhodayan, S., Elliott, J.M., Corpuz, R.T., Lazarus, R.A., Moran, P. J. Biol. Chem. (2003) [Pubmed]
  5. The tissue factor region that interacts with factor Xa in the activation of factor VII. Kirchhofer, D., Eigenbrot, C., Lipari, M.T., Moran, P., Peek, M., Kelley, R.F. Biochemistry (2001) [Pubmed]
  6. The tissue factor region that interacts with substrates factor IX and Factor X. Kirchhofer, D., Lipari, M.T., Moran, P., Eigenbrot, C., Kelley, R.F. Biochemistry (2000) [Pubmed]
  7. Epitope location on tissue factor determines the anticoagulant potency of monoclonal anti-tissue factor antibodies. Kirchhofer, D., Moran, P., Chiang, N., Kim, J., Riederer, M.A., Eigenbrot, C., Kelley, R.F. Thromb. Haemost. (2000) [Pubmed]
 
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