David J. Greenblatt
Tufts University School of Medicine
Tufts Medical Center
Department of Molecular Physiology and Pharmacology
Sackler Program in Pharmacology and Experimental Therapeutics
Name/email consistency: high
- Pharmacokinetic evaluation of eszopiclone : clinical and therapeutic implications. Greenblatt, D.J., Zammit, G.K. Expert. Opin. Drug. Metab. Toxicol (2012)
- Zolpidem for insomnia. Greenblatt, D.J., Roth, T. Expert. Opin. Pharmacother (2012)
- Pharmacokinetic profile of SKP-1041, a modified release formulation of zaleplon. Greenblatt, D.J., Harmatz, J.S., Walsh, J.K., Luthringer, R., Staner, L., Otmani, S., Nedelec, J.F., Francart, C., Parent, S.J., Staner, C. Biopharm. Drug. Dispos (2011)
- Mechanism of cytochrome P450-3A inhibition by ketoconazole. Greenblatt, D.J., Zhao, Y., Venkatakrishnan, K., Duan, S.X., Harmatz, J.S., Parent, S.J., Court, M.H., von Moltke, L.L. J. Pharm. Pharmacol. (2011)
- Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro. Greenblatt, D.J., Venkatakrishnan, K., Harmatz, J.S., Parent, S.J., von Moltke, L.L. Xenobiotica (2010)
- Analysis of drug interactions involving fruit beverages and organic anion-transporting polypeptides. Greenblatt, D.J. J. Clin. Pharmacol (2009)
- Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase. Greenblatt, D.J., Peters, D.E., Oleson, L.E., Harmatz, J.S., MacNab, M.W., Berkowitz, N., Zinny, M.A., Court, M.H. Br. J. Clin. Pharmacol (2009)
- Gender has a small but statistically significant effect on clearance of CYP3A substrate drugs. Greenblatt, D.J., von Moltke, L.L. J. Clin. Pharmacol (2008)
- Age and gender effects on the pharmacokinetics and pharmacodynamics of ramelteon, a hypnotic agent acting via melatonin receptors MT1 and MT2. Greenblatt, D.J., Harmatz, J.S., Karim, A. J. Clin. Pharmacol (2007)
- In vitro interactions of water-soluble garlic components with human cytochromes p450. Greenblatt, D.J., Leigh-Pemberton, R.A., von Moltke, L.L. J. Nutr. (2006)
- Dynamics and kinetics of a modified-release formulation of zolpidem: comparison with immediate-release standard zolpidem and placebo. Greenblatt, D.J., Legangneux, E., Harmatz, J.S., Weinling, E., Freeman, J., Rice, K., Zammit, G.K. J. Clin. Pharmacol (2006)
- Pharmocokinetics and pharmacodynamics of single-dose triazolam: electroencephalography compared with the Digit-Symbol Substitution Test. Greenblatt, D.J., Gan, L., Harmatz, J.S., Shader, R.I. Br. J. Clin. Pharmacol (2005)
- Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate. Greenblatt, D.J., Harmatz, J.S., von Moltke, L.L., Wright, C.E., Shader, R.I. Clin. Pharmacol. Ther. (2004)
- In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5. Patki, K.C., Von Moltke, L.L., Greenblatt, D.J. Drug Metab. Dispos. (2003)
- Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice. Greenblatt, D.J., von Moltke, L.L., Harmatz, J.S., Chen, G., Weemhoff, J.L., Jen, C., Kelley, C.J., LeDuc, B.W., Zinny, M.A. Clin. Pharmacol. Ther. (2003)
- Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences. Greenblatt, D.J., Harmatz, J.S., von Moltke, L.L., Wright, C.E., Durol, A.L., Harrel-Joseph, L.M., Shader, R.I. J. Pharmacol. Exp. Ther. (2000)
- Alprazolam-ritonavir interaction: implications for product labeling. Greenblatt, D.J., von Moltke, L.L., Harmatz, J.S., Durol, A.L., Daily, J.P., Graf, J.A., Mertzanis, P., Hoffman, J.L., Shader, R.I. Clin. Pharmacol. Ther. (2000)
- Differential impairment of triazolam and zolpidem clearance by ritonavir. Greenblatt, D.J., von Moltke, L.L., Harmatz, J.S., Durol, A.L., Daily, J.P., Graf, J.A., Mertzanis, P., Hoffman, J.L., Shader, R.I. J. Acquir. Immune Defic. Syndr. (2000)
- Kinetics and dynamics of lorazepam during and after continuous intravenous infusion. Greenblatt, D.J., von Moltke, L.L., Ehrenberg, B.L., Harmatz, J.S., Corbett, K.E., Wallace, D.W., Shader, R.I. Crit. Care Med. (2000)