The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

Table of contents

About

Terms

 

Evan D. Kharasch

Department of Anesthesiology

Division of Clinical and Translational Research

Washington University in St. Louis

St. Louis

USA

[email]@wustl.edu

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Anesthesiology, Division of Clinical and Translational Research, Washington University in St. Louis, St. Louis, USA. 2006 - 2013
  • Department of Anesthesiology, Washington University, 660 S. Euclid Ave, Campus Box 8054. 2006 - 2012
  • Department of Anesthesiology, University of Washington, Seattle, USA. 2005

References

  1. Role of cytochrome P4502B6 in methadone metabolism and clearance. Kharasch, E.D., Stubbert, K. J. Clin. Pharmacol (2013) [Pubmed]
  2. P-glycoprotein is a major determinant of norbuprenorphine brain exposure and antinociception. Brown, S.M., Campbell, S.D., Crafford, A., Regina, K.J., Holtzman, M.J., Kharasch, E.D. J. Pharmacol. Exp. Ther. (2012) [Pubmed]
  3. Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanil. Kharasch, E.D., Vangveravong, S., Buck, N., London, A., Kim, T., Blood, J., Mach, R.H. Clin. Pharmacol. Ther. (2011) [Pubmed]
  4. Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir. Kharasch, E.D., Hoffer, C., Whittington, D., Walker, A., Bedynek, P.S. Anesthesiology (2009) [Pubmed]
  5. Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity. Kharasch, E.D., Walker, A., Whittington, D., Hoffer, C., Bedynek, P.S. Drug. Alcohol. Depend (2009) [Pubmed]
  6. Sevoflurane formulation water content influences degradation by Lewis acids in vaporizers. Kharasch, E.D., Subbarao, G.N., Cromack, K.R., Stephens, D.A., Saltarelli, M.D. Anesth. Analg. (2009) [Pubmed]
  7. Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir. Kharasch, E.D., Mitchell, D., Coles, R., Blanco, R. Antimicrob. Agents Chemother. (2008) [Pubmed]
  8. Stereoselective bupropion hydroxylation as an in vivo phenotypic probe for cytochrome P4502B6 (CYP2B6) activity. Kharasch, E.D., Mitchell, D., Coles, R. J. Clin. Pharmacol (2008) [Pubmed]
  9. Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities. Kharasch, E.D., Bedynek, P.S., Walker, A., Whittington, D., Hoffer, C. Clin. Pharmacol. Ther. (2008) [Pubmed]
  10. Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: I. Evidence against CYP3A mediation of methadone clearance. Kharasch, E.D., Bedynek, P.S., Park, S., Whittington, D., Walker, A., Hoffer, C. Clin. Pharmacol. Ther. (2008) [Pubmed]
  11. Adverse drug reactions with halogenated anesthetics. Kharasch, E.D. Clin. Pharmacol. Ther. (2008) [Pubmed]
  12. Mutations in a molecule: the virtues of antagonism. Kharasch, E.D. Mayo Clin. Proc. (2008) [Pubmed]
  13. Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam. Kharasch, E.D., Walker, A., Isoherranen, N., Hoffer, C., Sheffels, P., Thummel, K., Whittington, D., Ensign, D. Clin. Pharmacol. Ther. (2007) [Pubmed]
  14. New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 2): Identification of nephrotoxic metabolites. Kharasch, E.D., Schroeder, J.L., Liggitt, H.D., Ensign, D., Whittington, D. Anesthesiology (2006) [Pubmed]
  15. New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 1): Identification of the nephrotoxic metabolic pathway. Kharasch, E.D., Schroeder, J.L., Liggitt, H.D., Park, S.B., Whittington, D., Sheffels, P. Anesthesiology (2006) [Pubmed]
  16. Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether ("compound A") in rats. Kharasch, E.D., Schroeder, J.L., Bammler, T., Beyer, R., Srinouanprachanh, S. Toxicol. Sci. (2006) [Pubmed]
  17. Influence of sevoflurane on the metabolism and renal effects of compound A in rats. Kharasch, E.D., Schroeder, J.L., Sheffels, P., Liggitt, H.D. Anesthesiology (2005) [Pubmed]
 
WikiGenes - Universities