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Lee A. Dawson

Psychiatry CEDD

GlaxoSmithKline

Harlow

[email]@gsk.com

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Affiliations

Psychiatry CEDD, GlaxoSmithKline, Harlow, UK. 2008
Psychiatry Centre of Excellence for Drug Discovery, GlaxoSmithKline, Essex, UK. 2006 - 2008

References

5-HT1 receptor augmentation strategies as enhanced efficacy: therapeutics for psychiatric disorders. Dawson, L.A., Bromidge, S.M. Curr. Top. Med. Chem (2008) [Pubmed]
In vitro and in vivo characterization of the non-peptide NK3 receptor antagonist SB-223412 (talnetant): potential therapeutic utility in the treatment of schizophrenia. Dawson, L.A., Cato, K.J., Scott, C., Watson, J.M., Wood, M.D., Foxton, R., de la Flor, R., Jones, G.A., Kew, J.N., Cluderay, J.E., Southam, E., Murkitt, G.S., Gartlon, J., Pemberton, D.J., Jones, D.N., Davies, C.H., Hagan, J. Neuropsychopharmacology (2008) [Pubmed]
Characterisation of the selective 5-HT1B receptor antagonist SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): in vivo neurochemical and behavioural evidence of anxiolytic/antidepressant activity. Dawson, L.A., Hughes, Z.A., Starr, K.R., Storey, J.D., Bettelini, L., Bacchi, F., Arban, R., Poffe, A., Melotto, S., Hagan, J.J., Price, G.W. Neuropharmacology (2006) [Pubmed]