Magang Shou
Department of Drug Metabolism
Merck Research Laboratories
West Point
PA 19486
USA
Name/email consistency: high
- Prediction of pharmacokinetics and drug-drug interactions from in vitro metabolism data. Shou, M. Curr. Opin. Drug. Discov. Devel (2005)
- Population pharmacokinetic modeling for enterohepatic recirculation in Rhesus monkey. Shou, M., Lu, W., Kari, P.H., Xiang, C., Liang, Y., Lu, P., Cui, D., Emary, W.B., Michel, K.B., Adelsberger, J.K., Brunner, J.E., Rodrigues, A.D. Eur. J. Pharm. Sci (2005)
- Substrate specificity and kinetic properties of seven heterologously expressed dog cytochromes p450. Shou, M., Norcross, R., Sandig, G., Lu, P., Li, Y., Lin, Y., Mei, Q., Rodrigues, A.D., Rushmore, T.H. Drug Metab. Dispos. (2003)
- A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4. Shou, M., Dai, R., Cui, D., Korzekwa, K.R., Baillie, T.A., Rushmore, T.H. J. Biol. Chem. (2001)
- Enzyme kinetics of cytochrome P450-mediated reactions. Shou, M., Lin, Y., Lu, P., Tang, C., Mei, Q., Cui, D., Tang, W., Ngui, J.S., Lin, C.C., Singh, R., Wong, B.K., Yergey, J.A., Lin, J.H., Pearson, P.G., Baillie, T.A., Rodrigues, A.D., Rushmore, T.H. Curr. Drug Metab. (2001)
- Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism. Shou, M., Lu, T., Krausz, K.W., Sai, Y., Yang, T., Korzekwa, K.R., Gonzalez, F.J., Gelboin, H.V. Eur. J. Pharmacol. (2000)
- Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives. Shou, M., Mei, Q., Ettore, M.W., Dai, R., Baillie, T.A., Rushmore, T.H. Biochem. J. (1999)
- Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver. Shou, M., Martinet, M., Korzekwa, K.R., Krausz, K.W., Gonzalez, F.J., Gelboin, H.V. Pharmacogenetics (1998)
