Disease relevance of fluorobenzene

• The mutagenicity of 21 chloro- or fluoronitrobenzene compounds and 9 chloro- or fluorobenzene compounds in Salmonella typhimurium (strains TA98, TA1538, TA1537, TA100 and TA1535) was examined [1].

High impact information on fluorobenzene

• The skin tumor promoter phenol also reversibly inhibited neurite outgrowth, while comparable concentrations of the nonpromoting but structurally related compounds benzene and fluorobenzene did not [2].
• The X-ray crystal structures of fluorobenzene 50c and benzoquinone 54 inhibitors complexed with the TF/VIIa enzyme will also be described [3].
• The in vivo regioselectivity of the hydroxylation of fluorobenzene was not significantly influenced by changes in the cytochrome P-450 enzyme pattern [4].
• Liquid chromatography-mass spectrometry analysis showed that 4-fluorocatechol and catechol were formed as intermediates during fluorobenzene degradation by cell suspensions [5].
• [formula: see text] Complexes formed between fluorobenzene and N-methylformamide or benzene have been used as models of the interaction of fluoroaromatic drugs with carbonic anhydrase II [6].

Associations of fluorobenzene with other chemical compounds

• Additional experiments were performed to investigate whether the regioselectivity of the aromatic hydroxylation of the C4-substituted fluorobenzene model compounds was influenced by changes in the cytochrome P450 enzyme pattern [7].
• A decrease in selectivity was observed going from fluorobenzene to iodobenzene using PDMS/DVB and PDMS/Carboxen fibers [8].
• The low-resolution (resolution: 0.6 nm) fluorescence spectra of fluorobenzene derivatives, o-, m- and p-fluorotoluene (o-, m- and p-FT) were observed to investigate intramolecular vibrational energy redistribution (IVR) under controlled electron impact [9].

Gene context of fluorobenzene

• The coupling of T4MO activity with tyrosinase activity in the presence of fluorobenzene resulted in the formation of a colored product absorbing maximally at 480 nm [10].
• Studies on modified DNA oligomers and polymerase reactions have previously demonstrated that canonical nucleobases can exhibit stable and even selective pairing with shape-complementary fluorobenzene nucleotides [11].

Analytical, diagnostic and therapeutic context of fluorobenzene

• Photodissociation of both fluorobenzene and d(5)-fluorobenzene at 193 nm under collision-free conditions has been studied in separate experiments using multimass ion imaging techniques [12].

References