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Chemical Compound Review:

RETENE 1-methyl-7-propan-2-yl- phenanthrene

Synonyms: Reten, RETENE, 98%, CCRIS 3180, NCI-C55390, AG-J-93145, ...

Brinkworth, L.C. et al., Häkkinen, J. et al., Huovinen, P.S. et al.

Huovinen, Soimasuo, Oikari, Häkkinen, Vehniäinen, Oikari,

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Disease relevance of RETENE

The effects of UV radiation on the acute toxicity of retene (7-isopropyl-1-methylphenanthrene) to Daphnia magna Straus were studied [1].
Further, a comparative investigation on the acute phototoxicity of retene (7-isopropyl-1-methylphenanthrene), a PAH compound recently revealed to posses UV-B-induced phototoxicity in larval coregonids, was conducted with pike larvae [2].

High impact information on RETENE

Early life stages of rainbow trout were exposed to different regimes of water-borne retene (7-isopropyl-1-methylphenanthrene) to determine if there is an ontogenic stage particularly sensitive to retene toxicity, and if cytochrome P-4501A (CYP1A) induction is a forerunner to blue sac disease (BSD), the syndrome of toxicity [3].

References

Photoinduced toxicity of retene to Daphnia magna under enhanced UV-B radiation. Huovinen, P.S., Soimasuo, M.R., Oikari, A.O. Chemosphere (2001) [Pubmed]
High sensitivity of northern pike larvae to UV-B but no UV-photoinduced toxicity of retene. Häkkinen, J., Vehniäinen, E., Oikari, A. Aquat. Toxicol. (2004) [Pubmed]
CYP1A induction and blue sac disease in early developmental stages of rainbow trout (Oncorhynchus Mykiss) exposed to retene. Brinkworth, L.C., Hodson, P.V., Tabash, S., Lee, P. J. Toxicol. Environ. Health Part A (2003) [Pubmed]

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