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Chemical Compound Review

AG-F-21831     N-(4-aminophenyl)sulfonyl-N- (4,6...

Synonyms: CTK4H4116, AR-1J6954, AC1L336E, AC1Q6V7V, 35255-37-9, ...
 
 
 
 
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High impact information on Acetylsulfadimidine

  • Kinetic analysis of the plasma concentration-time profiles for SMZ indicated that HC treatment significantly increased the rate of acetylation of SMZ without altering the renal clearances or volumes of distribution for either parent drug or the N-acetyl metabolite N-acetylsulfamethazine (NASMZ) [1].

References

  1. Induction of sulfamethazine acetylation by hydrocortisone in the rabbit. Reeves, P.T., Minchin, R.F., Ilett, K.F. Drug Metab. Dispos. (1988) [Pubmed]
 
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