Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Of-314 2-diethylaminoethyl 1-azabicyclo[2.2.2]oct...

Synonyms: CTK8D7250, AR-1C9015, LS-143099, BRN 0194720, AC1L3DY4, ...

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Of-314

Of 314 patients with this skin lesion, almost half developed multiple annular secondary lesions; some patients had evanescent red blotches or circles, malar or urticarial rash, conjunctivitis, periorbital edema, or diffuse erythema [1].
Of 314 patients with proved pseudogout, 9 had a separate serious disease in the same joint: 5 had septic arthritis, 2 rheumatoid arthritis, 1 psoriatic arthritis, and 1 hypertrophic pulmonary osteoarthropathy [2].
Of 314 cider samples tested, 11 (4%) were found to contain E. coli [3].
RESULTS: Of 314 patients admitted, 65 prospectively met the criteria for acute respiratory distress syndrome [4].
Of 314 cases resulting from this review, organ procurement efforts yielded 10 patients with a diagnosis of brain tumor [5].

Psychiatry related information on Of-314

RESULTS: Of 314 (88% of eligible) patients who were recruited, 199 (63%) were male and 63 (20%) had depressive disorders [6].

High impact information on Of-314

Of 314 youths, 111 (35.4%) who received stimulant medication did not meet DSM-IV criteria for ADHD [7].
Of 314 mutants, 182 (58%) had independent mutations, 74 (23.5%) appeared clonal, and 58 (18.5%) showed no cII mutations [8].
Of 314 cases presenting with focal neurology, 83 (26.4%) showed significant findings [9].
Of 314 fetuses scanned, a four-chamber view was obtained in 290; a hypoechoic rim was present in 94% of these [10].
Of 314 patients undergoing TVT and followed for up to 50 months only 1 suffered genital prolapse, with de novo grade 2 cystocele, rectocele and uterine prolapse, diagnosed 3 months after the operation [11].

Analytical, diagnostic and therapeutic context of Of-314

RESULTS: Of 314 patients, 159 comprised the control group and 155 the FAM2 group [12].
Of 314 plasma samples referred for LA screening, positive results were found in 62 by both APTT and ELISA [13].
Of 314 chemotherapy cycles delivered (median 5 in both groups), dose reduction was required more frequently in the DF group, being 9 and 19%, respectively (P<0.01) [14].

References

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Pseudogout masking other arthritides. Zyskowski, L.P., Silverfield, J.C., O'Duffy, J.D. J. Rheumatol. (1983) [Pubmed]
Prevalence of Escherichia coli in apple cider manufactured in Connecticut. Dingman, D.W. J. Food Prot. (1999) [Pubmed]
Comparison of 3 methods of detecting acute respiratory distress syndrome: clinical screening, chart review, and diagnostic coding. Howard, A.E., Courtney-Shapiro, C., Kelso, L.A., Goltz, M., Morris, P.E. Am. J. Crit. Care (2004) [Pubmed]
Factors influencing organ placement efforts in donors with brain tumors. Lewis, D.D., Vidovich, R.R. Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO). (1996) [Pubmed]
The risk factors for depression in first myocardial infarction patients. Dickens, C.M., Percival, C., McGowan, L., Douglas, J., Tomenson, B., Cotter, L., Heagerty, A., Creed, F.H. Psychological medicine. (2004) [Pubmed]
ADHD medication use in a population-based sample of twins. Reich, W., Huang, H., Todd, R.D. Journal of the American Academy of Child and Adolescent Psychiatry. (2006) [Pubmed]
Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice. Harbach, P.R., Zimmer, D.M., Filipunas, A.L., Mattes, W.B., Aaron, C.S. Environ. Mol. Mutagen. (1999) [Pubmed]
Is primary care access to CT brain examinations effective? Benamore, R.E., Wright, D., Britton, I. Clinical radiology. (2005) [Pubmed]
The peripheral hypoechoic rim of the fetal heart. Brown, D.L., Cartier, M.S., Emerson, D.S., Shanklin, D.R., Smith, W.C., Felker, R.E. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. (1989) [Pubmed]
Low incidence of post-TVT genital prolapse. Neuman, M. International urogynecology journal and pelvic floor dysfunction. (2003) [Pubmed]
Final results of a phase III clinical trial of adjuvant chemotherapy with the modified fluorouracil, doxorubicin, and mitomycin regimen in resectable gastric cancer. Lise, M., Nitti, D., Marchet, A., Sahmoud, T., Buyse, M., Duez, N., Fiorentino, M., Dos Santos, J.G., Labianca, R., Rougier, P. J. Clin. Oncol. (1995) [Pubmed]
Quantitation of anticephalin antibodies in a computer-assisted enzyme-linked immunosorbent assay (ELISA): relation to lupus anticoagulant. Sletnes, K.E., Keirung, G., Wisløff, F. Thromb. Res. (1990) [Pubmed]
Paclitaxel versus docetaxel for advanced gastric cancer: a randomized phase II trial in combination with infusional 5-fluorouracil. Park, S.H., Lee, W.K., Chung, M., Lee, Y., Han, S.H., Bang, S.M., Cho, E.K., Shin, D.B., Lee, J.H. Anticancer Drugs (2006) [Pubmed]

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